Virgin Islands Department of Health Tuberculosis Program - Project Abstract Summary The Virgin Islands Tuberculosis Elimination Program provides programmatic oversight, facilitates clinical consultations, and provides education and training resources throughout the Virgin Islands. The Tuberculosis Elimination Program utilizes a portion of federal funding to facilitate staffing and program activities to four islands, St. Thomas, St. John, Water Island, and St. Croix. We provide TB services (screening, testing, treatment, and case management, etc.) to residents and visitors of the Virgin Islands. The mission is to eliminate TB in Virgin Islands. Elimination of TB in Virgin Islands is predicated on the implementation of three (3) priority strategies for controlling and preventing TB, as recommended by the Advisory Council for the Elimination of Tuberculosis (ACET) that include: (1) identifying and fully treating persons who have active TB disease; (2) finding and screening persons who are contacts to TB cases to determine if they are infected with Mycobacterium tuberculosis or have active TB, and providing appropriate treatment; and (3) targeting populations at high-risk for infection and disease to detect infected persons and provide TB infection (TBI) therapy when appropriate to prevent progression to active TB. The Virgin Islands Tuberculosis Elimination Program is committed to progressing toward the national targets set forth in the National TB Indicators Project and strives to develop evaluation strategies to address those indicators not being met. In addition, we are committed to identifying, screening, testing, and treating those individuals at high risk for exposure to Mycobacterium tuberculosis, those at high risk for progression to active TB disease if exposed, and those populations experiencing health disparities and disproportionately affected by TB disease and TB infection (TBI). The Virgin Islands Tuberculosis Elimination Program is applying for funding under the Tuberculosis Elimination and Laboratory Cooperative Agreement CDC-RFA-PS-25-0003 to assist with addressing the strategies and implementing the activities identified in this application. Funding for Prevention and Control (P&C) and Human Resources Development (HRD) will allow for continued and new activities that be measured by evaluation of progress toward short-term and intermediate outcomes outlined in the funding announcement. Progress toward these short-term and intermediate outcomes will lead to a decreased TB incidence overall and among those populations at higher risk and those disproportionately affected by TB disease and TB infection.