The Maryland Emerging Infections Program (MD EIP) proposes to sustain and enhance its collaboration with CDC, other federal partners, and other EIP sites to prevent, control, and monitor the public health impact of infectious diseases. At the state level, these activities will continue to be conducted in collaboration with other units within the Maryland Department of Health (MDH), local health departments, hospital and nursing home infection preventionists, public health and clinical laboratories, healthcare providers, and public health academic partners (Johns Hopkins Bloomberg School of Public Health; University of Maryland, Baltimore; and Morgan State University). Specifically, the MD EIP will continue to participate in the Active Bacterial Core surveillance (ABCs), the Foodborne Diseases Active Surveillance Network (FoodNet), the Healthcare-Associated Infections – Community Interface (HAIC), the Influenza Surveillance Network (FluSurv-NET), the Respiratory Syncytial Virus Surveillance Network (RSV-NET), and Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET) activities. In support of MDH workforce development efforts, training opportunities will also be provided for state public health epidemiologists and laboratory scientists, local health department staff, and public health graduate students. In addition to these on-going efforts, the MD EIP will conduct activities to enhance interoperable data exchange and bioinformatics; to understand systemic health and social inequities to advance public health practices and policies addressing these issues; and prepare for an increase in response efforts for emerging or re-emerging infectious disease(s), outbreak scenarios, or other public health threats.