The Connecticut Emerging Infections Program - Connecticut Emerging Infections Program: Project Abstract Emerging Infections Program Application FOA# CDC-RFA-CK24-2401 The Connecticut Emerging Infections Program (CT EIP) was established in 1995 and is a joint effort between the State of Connecticut Department of Public Health, the Yale School of Public Health (YSPH) and the Centers for Disease Control and Prevention. The CT EIP receives all of its funding through a cooperative agreement with the CDC and has been funded from 1995–2023. The goals of the EIP network are to assess the public health impact of emerging and re-emerging infections and to evaluate methods for their prevention and control. The CT EIP encompasses twelve activities conducted by DPH and YSPH as described below. 1. Infrastructure and Data Modernization supports establishment and maintenance of staff and activities that are essential to assuring general EIP infrastructure. Key activities include enhanced cross-cutting scientific, programmatic, and business management for conducting EIP programmatic activities; flexibility and efficiency for responding to emerging infections and public health emergencies; enhanced training and workforce development; and modernized and improved EIP information systems for collection and electronic exchange of data to inform public health policy and practices. 2,3. Surveillance and Reporting 1 and 2 potential funding would provide additional epidemiologic, laboratory, and/or health information systems surge capacity necessary for enhanced public health surveillance or applied research activities to rapidly respond to emerging or re-emerging infectious disease(s), outbreaks, or other public health threats. 4. Influenza Hospitalization Surveillance Network (FluSurv-NET) conducts population-based surveillance to provide near real-time weekly rates of laboratory-confirmed influenza-associated hospitalizations by age, sex, and race/ethnicity during each influenza season. Data will be used to determine the timing and severity of influenza seasons and to guide future influenza prevention and control strategies. 5. Respiratory Syncytial Virus-Associated Hospitalizations (RSV-NET) conducts surveillance on laboratory-confirmed, RSV-associated hospitalizations, including those resulting in ICU admission or death, among children and adults. 6. COVID-19-Associated Hospitalization Surveillance (COVID-NET) conducts population-based surveillance for laboratory-confirmed COVID-19-associated hospitalizations among children and adults. COVID-NET, along with RSV-NET, and FluSurv-NET, comprise the Respiratory Virus Hospitalization Surveillance Network (RESP-NET). 7. Active Bacterial Core Surveillance (ABCs) conducts active population-based laboratory surveillance to assess the public health impact of emerging invasive bacterial disease due to Streptococcus pneumoniae, group A Streptococcus, group B Streptococcus, Haemophilus influenzae, and Neisseria meningitidis to evaluate methods for their prevention and control. 8. Foodborne Diseases Active Surveillance Network (FoodNet) conducts active population-based surveillance to determine the burden of illness due to pathogens commonly transmitted through food including Campylobacter, Listeria, Salmonella, Shiga toxin-producing E. coli (STEC) O157 and non-O157, Shigella, Vibrio, Yersinia, and Cyclospora to identify risk factors for infection. 9. Healthcare-Associated Infections – Community Interface (HAIC) conducts population-based surveillance for specific healthcare associated infection (HAI) pathogens and special projects such as HAI and antimicrobial use prevalence surveys to inform prevention strategies for HAIs, antimicrobial-resistant and other healthcare-associated pathogens. 10. HPV Vaccine Impact Monitoring Project (HPV-IMPACT) conducts population-based surveillance for high-grade cervical lesions and characterizes HPV strains associated with these lesions to monitor the early impact of HPV vaccination and to