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Global Healthcare Detection and Response: Antimicrobial Resistance in Invasive Bacterial and Respiratory Pathogens in Burkina Faso, Niger, and Togo

Award Number: NU3HCK000016
ORGANIZATION: NATIONAL CENTER FOR ZOONOTIC, VECTOR-BORNE, AND ENTERIC DISEASES
OPDIV: CDC
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: HEALTH SERVICES
PERIOD OF PERFORMANCE START DATE: 09/30/2021
PERIOD OF PERFORMANCE END DATE: 09/29/2027

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Global Healthcare Detection and Response: Antimicrobial Resistance in Invasive Bacterial and Respiratory Pathogens in Burkina Faso, Niger, and Togo - Across Africa, bacterial meningitis is associated with high morbidity and mortality, particularly among populations in the meningitis belt. Prognosis for infection with bacterial meningitis varies by strain and patient demographic factors, with poorer outcomes associated with late presentation, lack of access to diagnostics, inadequate treatment modalities, and HIV comorbidity. Growing data from African settings, including countries in the meningitis belt, indicate the emergence of antimicrobial resistance (AMR) in the bacterial meningitis pathogens Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Burkina Faso and Northern Togo fall within the meningitis belt, experiencing recurring outbreaks of endemic bacterial meningitis. The distribution and epidemic potential of bacterial meningitis strains in these regions vary over time; limited surveillance data makes it difficult to obtain timely, reliable estimates of disease burden and AMR emergence. Delivering appropriate, timely medical care to populations at risk of bacterial meningitis depends on effective health systems that have the capacity to support AMR detection and data management to detect, surveil, and respond to meningitis and associated infections. Effective detection and surveillance measures are critical to mitigate existing AMR and limit its further emergence. To assure that AMR is detected, tracked, and empirically mitigated for bacterial meningitis strains and other infections, health systems must contain well-integrated and functional laboratory services capable of collecting, analyzing, and communicating key surveillance data. To fulfill the need for comprehensive, accessible data for clinical and public health decision-making, national health stakeholders and international partners must advance initiatives to guide the proper use of antimicrobials and coordinate critical surveillance activities to identify and respond to local resistance profiles. In recent years, the governments of Burkina Faso and Togo have increasingly invested in public health and laboratory system coordination for AMR detection, surveillance, and response, establishing national AMR focal point roles and national reference laboratories for AMR to oversee coordinated response efforts. Each country is at a different level of operation, with Burkina Faso and Niger implementing well-established national AMR programs, while Togo is starting to build a program established only recently. Both countries are progressively establishing and reinforcing strategic collaborations to address AMR. These collaborations have enabled AMR capacity building, while adding further complexity to an already complex issue requiring engagement from the sectors of human health, animal health, environment and agriculture, and civil society. GSSHealth understands local and regional contexts of ongoing AMR capacity building efforts, particularly for laboratory diagnosis and surveillance. Our partner Jhpiego, an affiliate of Johns Hopkins University offering clinical and programmatic support, has offices in Burkina Faso and Togo. Together, we are supporting the CDC and partner ministries to strengthen their meningitis AMR detection and response initiatives and fill gaps. This project aims to improve the detection and response to AMR threats identified during outbreaks of bacterial meningitis in three select countries of the meningitis belt of West Africa. This aim will be achieved by enhancing current surveillance programs to expand AMR testing using classical bacteriology and molecular methodologies including next-generation sequencing (NGS). The findings of these efforts will be used to inform clinical decision making and planning for the response to the ongoing threat of serious bacterial meningitis outbreaks both within partner countries and as part of broader, regional efforts to track patterns of disease.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2027 ( Subtotal = $0 )
2027	2026	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	03	5	10/8/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2027	2025	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	03	5	10/8/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2027	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	03	5	10/8/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $0

Issue Date FY: 2026 ( Subtotal = $180,000 )
2026	2026	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	5	8/24/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$180,000
2026	2025	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	5	8/24/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2026	2025	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	5	3/17/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2026	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	5	8/24/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2026	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	5	3/17/2026	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $180,000

Issue Date FY: 2025 ( Subtotal = $250,000 )
2025	2025	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	5	8/18/2025	NON-COMPETING CONTINUATION	$250,000
2025	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	4	4/11/2025	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2025	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	4	11/12/2024	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2025	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	03	4	6/30/2025	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2025	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST # F1	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	5	8/18/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $250,000

Issue Date FY: 2024 ( Subtotal = $500,000 )
2024	2024	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	4	7/2/2024	NON-COMPETING CONTINUATION	$500,000
2024	2023	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	3	11/16/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2024	2023	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	3	2/23/2024	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2024	2022	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	3	11/16/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2024	2022	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	3	2/23/2024	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2024	2021	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	3	2/23/2024	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2024	2021	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	3	11/16/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $500,000

Issue Date FY: 2023 ( Subtotal = $500,000 )
2023	2023	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	3	7/5/2023	NON-COMPETING CONTINUATION	$500,000
2023	2022	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	2	11/10/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2022	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	03	2	9/11/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2022	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	3	7/5/2023	NON-COMPETING CONTINUATION	$0
2023	2022	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	2	3/3/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2021	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	3	7/5/2023	NON-COMPETING CONTINUATION	$0
2023	2021	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	02	2	3/3/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2021	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	2	11/10/2022	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2023	2021	GLOBAL SCIENTIFIC SOLUTIONS FOR HEALTH LLC	16 W READ ST	BALTIMORE	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	03	2	9/11/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $500,000

Issue Date FY: 2022 ( Subtotal = $500,000 )
2022	2022	Global Scientific Solutions for Health LLC	16 West Read Street	Baltimore	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	2	7/8/2022	NON-COMPETING CONTINUATION	$500,000
2022	2021	Global Scientific Solutions for Health LLC	16 West Read Street	Baltimore	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	2	7/8/2022	NON-COMPETING CONTINUATION	$0
2022	2021	Global Scientific Solutions For Health Llc	16 West Read Street	Baltimore	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	01	1	11/30/2021	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $500,000

Issue Date FY: 2021 ( Subtotal = $500,000 )
2021	2021	Global Scientific Solutions for Health LLC	16 West Read Street	Baltimore	MD	21201	BALTIMORE CITY	USA	Protecting and Improving Health Globally: Building and Strengthening Public Health Impact, Systems, Capacity and Security	00	1	9/16/2021	NEW	$500,000
														Subtotal = $500,000

Grand Total All Awards = $2,430,000

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Global Healthcare Detection and Response: Antimicrobial Resistance in Invasive Bacterial and Respiratory Pathogens in Burkina Faso, Niger, and Togo

Award Number: NU3HCK000016

ORGANIZATION: NATIONAL CENTER FOR ZOONOTIC, VECTOR-BORNE, AND ENTERIC DISEASES

OPDIV: CDC

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: HEALTH SERVICES

PERIOD OF PERFORMANCE START DATE: 09/30/2021

PERIOD OF PERFORMANCE END DATE: 09/29/2027

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