Strengthening Wabanaki Public Health Systems - Wabanaki Public Health and Wellness (WPHW) serves the Wabanaki, the People of the First Light; Mi’kmaq Nation, Houlton Band of Maliseet Indians, Passamaquoddy at Pleasant Point, Passamaquoddy at Indian Township, and Penobscot Nation. The indigenous population in Maine is estimated at over 13,000 people, most living on or near one of the 5 reservations spread over three large rural counties (Aroostook, Washington, and Penobscot). WPHW’s mission is to provide community-driven, culturally centered public health and social services to all Wabanaki communities and people while honoring Wabanaki cultural knowledge, cultivating innovation, and fostering collaboration. Wabanaki traditions, language, and culture guide our approach and describe the ways we live in harmony with each other and the land we collectively share. Wabanaki Public Health and Wellness seeks funding through the CDC Strengthening Public Health Systems grant to address the persistent disparities in health outcomes faced by tribal people in Maine. Despite advancements in public health, indigenous populations continue to experience disproportionately high rates of morbidity and mortality, exacerbated by the historical and ongoing effects of colonization, social inequities, systemic marginalization, and a lack of Tribal sovereignty and self-determination. This grant proposal aims to address the pressing need to strengthen and empower WPHW’s ability to respond to public health needs and emergencies by identifying and implementing culturally appropriate strategies that address the unique challenges faced by Wabanaki people. By engaging in a collaborative and community-driven approach, we aim to enhance capacity through focusing on organizational health, workforce building, and promotion of sustainable solutions. This aim will improve health outcomes, reduce health disparities, and promote health equity for Wabanaki communities.