Category C: Community Health Centers - This application is being submitted in response to the CDC-RFA-PW-24-0080 Notice of Funding Opportunity. As the nation’s leading, nationwide, voluntary health organization focused on cancer, the American Cancer Society (ACS) is ideally positioned to provide capacity building assistance (CBA) to community health centers (Category C- Public Health System Components) towards the reduction of disparities in cancer prevention and screening. ACS has decades-long history of providing capacity building assistance to Community Health Centers (CHCs), including education on quality improvement processes, activities to advance health equity, and development and dissemination of evidenced-based resources. Broad, national dissemination of CBA will be accelerated through the efforts of 139 ACS field team members who work with more than 344 CHCs (including Indian Health Clinics), 50 state primary care associations, and 50 state health departments across the country. Our team’s longstanding and trusted relationships will facilitate a seamless and immediate integration of capacity building assistance made possible through this funding opportunity. ACS will measure the impact of CBA through progress towards the following outcomes: Short-term - Increasing availability of and access to CBA services and products [at CHCs] that address policy and programs [to improve cancer outcomes and reduce cancer inequities]; and Intermediate - Increased awareness and understanding of recommended processes, policies, programs, and practices [within CHC policy and programs to improve cancer outcomes and reduce cancer inequities]. To achieve these outcomes, ACS will execute activities within the Strategic Area of “Policy and Programs” to empower CHCs to develop, improve, and use evidence-based and promising practices in policies, processes, and programs aimed at improving the health of the community, addressing disparities, and increasing equity. Activities will include: engaging partners through the establishment of a National Advisory Council comprised of subject matter experts from multiple sectors; assessing CHC teams’ training and education needs; developing products to equitably advance recommended evidence-based policies, processes, programs, and practices within CHCs; delivering quality training, tools, and technical assistance that addressees identified CHC training and education needs; and disseminating key findings, lessons learned, and best practices widely among CHCs.