Develop, Implement, and Sustain High-Quality Comprehensive Facility and Community-Based HIV 95-95-95 Cascade Activities for Children, Adolescents, and Adults in Cameroon under the President's Emerge - Since pivoting to the district health system in the mid-1990s, the government of the Republic of Cameroon (GRC) has continued to make efforts, with support from various technical and financial partners, including multiple USG agencies to build a robust health system. For over 20 years now CDC-Cameroon has been strengthening various sectors of the health system and since 2011, with PEPFAR funds, CDC (through its IPs among which the Cameroon Baptist Convention Health board (CBCHB)) has been leading efforts to strengthen Cameroon’s national HIV response by supporting direct service delivery (DSD) as well as technical Assistance (TA). CDC’s contribution includes support for governance and leadership, management and development of tools enabling the country to be on course for HIV epidemic control following the UNAIDS 95-95-95 treatment goals (95,8%, 93,3%, 89,2% respectively). Notwithstanding this progress, according to COP21 report, the country is still in a mixed generalized and concentrated HIV epidemic in specific sub, priority, at-risk and KP groups - compounded by a weak health system. This NOFO presents an opportunity for the CBCHB, an impactful indigenous organization and technical partner of the GRC in the HIV response for over 30 years now; Family Health International (FHI360), a leading international public health, development, and research organization, and Care and Health Program (CHP), a local NGO that has been involved in community health promotion and community systems building for over two decades, to work as a Consortium and support GRC’s health system strengthening efforts. This Consortium will help the GRC strengthen and maintain a robust and more responsive health system to effectively deliver a comprehensive package of high-quality HIV/TB services to relevant target groups including PPs such as children and adolescents, other subpopulations like PBFW, AGYW/ABYM, men, and crisis-affected internally displaced populations and KPs. Building on respective member’s rich experiences, this Consortium will collaborate with multiple partners/stakeholders and actors at all levels of the health system in the country to develop a well-balanced, highly impactful DSD and HSS package using evidenced based strategies like Total Quality Leadership and Accountability (TQLA) and the Gender Equality Social Inclusion (GESI) to analyze and address system gaps and equity barriers. The Consortium’s approach will ensure greater community engagement and strengthen MOH leadership especially at the operational level (district approach) to achieve a more resilient health system generally, and more specifically, to optimize access and uptake of HIV services especially for PPs and KPs to enable Cameroon achieve sustained HIV epidemic control by 2030.