Friday, April 26, 2024
4/26/2024
The overall goal of this project is to maintain a hospital-based birth defect(BD) surveillance program to determine the prevalence of major external birth defects and to conduct a case-control study to determine the maternal risk factors for birth defects among the newborns in four hospitals in Kampala, Uganda. The purpose of this grant was to continue implementing the BD surveillance project and conduct the case-control study. The purpose of this birth defect surveillance system is to provide a mechanism to determine if the maternal use of dolutegravir, cotrimoxazole, and other medications in early pregnancy are associated with a higher risk of birth defects in newborns and other adverse pregnancy outcomes. The surveillance will continue to provide background rates of major external birth defects as the transition to dolutegravir or other new ARVs increases as an effective treatment to eliminate mother-to-child transmission of HIV. This surveillance provides a unique opportunity to strengthen referral and linkage to partners who provide care and support for children identified with BD. Over the five years of the project, the surveillance team will work in collaboration with the Uganda Ministry of Health (MoH) and key stakeholders to incorporate BD surveillance into the national data information system to ensure sustainability after the end of the project.
HHS’ Tracking Accountability in Government Grants System (TAGGS) website provides access to detailed descriptions of grants, loans, aggregated direct payments and other types of financial assistance awarded by the HHS Operating Divisions (OPDIVs) and the Office of the Secretary Staff Divisions (STAFFDIVs).
