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Assessing health outcomes of polysubstance use during pregnancy through EHR data Component A

Award Number: NU01DD000028
ORGANIZATION: NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES (NCBDDD)
OPDIV: CDC
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: HEALTH SERVICES
PERIOD OF PERFORMANCE START DATE: 09/30/2023
PERIOD OF PERFORMANCE END DATE: 09/29/2027

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Assessing health outcomes of polysubstance use during pregnancy through EHR data Component A - There has been an increase in the concurrent use of two of more substances (i.e., polysubstance use) in pregnant individuals over the last decade in the United States. Polysubstance use during pregnancy can result in substantial health complications for the pregnant individual as well as long-term impacts on the health of their infants such as neonatal abstinence syndrome. Healthcare disparities in treatment access for substance use because of social determinants of health result in minority populations facing a disproportionate burden of these adverse health outcomes. Developing comprehensive care programs sensitive to the needs of these high-priority populations first requires understanding the true scope of the problem and characteristics of the patient population comprising pregnant individuals and their infants. Thus, the aim of our project is to apply a rigorous informatics approach to collect data about polysubstance use in pregnancy and its health outcomes on the pregnant individual and their children. Specifically, we will collaborate with the CDC and other experts in maternal and child health, substance use, informatics, and epidemiology to define and identify dyads of the high-priority population of pregnant individuals with polysubstance use and their infants using data from the electronic health record spanning a period of at least 5 years (2016-2021). Data will be abstracted, reviewed for accuracy, completeness, and other measures of data quality, and reported to the CDC using secure file exchange to protect patient privacy. Throughout the lifecycle of the project, we will use several measures to monitor and evaluate our performance to ensure we are meeting the public health priorities of the CDC and other agencies. Funding extensions beyond year 1 will enable us to expand data gathering and reporting for datasets beyond 2021 and to other measures impacting polysubstance use in pregnancy (e.g., intimate partner violence), thus helping capture a multi-system perspective on the topic. This grant will have a direct impact on healthcare practice and research because its work activities and findings will help improve informatics capabilities to conduct maternal and infant health surveillance and enable earlier detection of emerging threats, establish collaborations between experts in maternal and infant health, and enable data and knowledge sharing of methods, best practices, and findings to ultimately devise strategies to minimize the impact of polysubstance use in pregnancy on maternal and infant health in the US.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $398,768 )
2025	2025	MEDSTAR HEALTH RESEARCH INSTITUTE INC.	10980 Grantchester Way 7th FL	Columbia	MD	21044	HOWARD	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	00	3	9/17/2025	NON-COMPETING CONTINUATION	$398,768
2025	2024	MEDSTAR HEALTH RESEARCH INSTITUTE INC.	10980 Grantchester Way 7th FL	Columbia	MD	21044	HOWARD	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	00	3	9/17/2025	NON-COMPETING CONTINUATION	$0
2025	2024	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	01	2	11/7/2024	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2025	2023	MEDSTAR HEALTH RESEARCH INSTITUTE INC.	10980 Grantchester Way 7th FL	Columbia	MD	21044	HOWARD	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	00	3	9/17/2025	NON-COMPETING CONTINUATION	$0
2025	2023	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	01	2	11/7/2024	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
														Subtotal = $398,768

Issue Date FY: 2024 ( Subtotal = $394,221 )
2024	2024	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	00	2	8/13/2024	NON-COMPETING CONTINUATION	$394,221
2024	2023	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	01	1	11/8/2023	ADMINISTRATIVE SUPPLEMENT ( + OR - ) (DISCRETIONARY OR BLOCK AWARDS)	$0
2024	2023	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	00	2	8/13/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $394,221

Issue Date FY: 2023 ( Subtotal = $410,647 )
2023	2023	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Birth Defects and Developmental Disabilities - Prevention and Surveillance	00	1	8/31/2023	NEW	$410,647
														Subtotal = $410,647

Grand Total All Awards = $1,203,636

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Assessing health outcomes of polysubstance use during pregnancy through EHR data Component A

Award Number: NU01DD000028

ORGANIZATION: NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES (NCBDDD)

OPDIV: CDC

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: HEALTH SERVICES

PERIOD OF PERFORMANCE START DATE: 09/30/2023

PERIOD OF PERFORMANCE END DATE: 09/29/2027

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