The Ohio State University Wexner Medical Center (OSUWMC) is pleased to submit this
application as a clinical site for its surveillance network. The faculty and staff of the
Substance Abuse Treatment & Prevention Program (STEPP) at the OSUWMC and Center for Perinatal Research at Nationwide Children’s Hospital (NCH) are well positioned to fulfil the scope of work for this project. Our overall objective is to sustain, improve, and expand current surveillance efforts by leveraging our established linked pregnant people-infant longitudinal data to ensure timely reporting of key exposures and outcomes, improve data quality, share evolving outcome data, innovate clinical strategies, and to contribute to a strong collaborative network.
The OSU-NCH team has experience collecting longitudinal health outcomes data associated with opioid use disorder for linked pregnant person-infant dyads. Through participation in the MATernaL and Infant NetworK to Understand Outcomes Associated with Treatment for Opioid Use Disorder During Pregnancy (MAT-LINK) project since its initiation in 2020, we have built the infrastructure to use our linked adult and pediatric electronic health records (EHR) to gather important surveillance data from the prenatal and postpartum periods through childhood.
The primary exposure and outcome of interest for our application are medication for opioid use disorder (MOUD) and neonatal abstinence syndrome (NAS), as supported by our specific expertise and recent MAT-LINK participation, outlined in this application. Building on existing partnerships with local community organizations and service providers (e.g., Maryhaven, Ohio Early Intervention, Partners for Kids), we will improve surveillence data collection between our clinical site and these public health partners, leading to increased access and availability of EHR and public health data. With an established infrastructure and key personnel with experience accessing and submitting data, we can help expand and strengthen this collaborative surveillance system which can be leveraged to improve timely reporting of key exposures and outcomes and to evaluate emerging threats during pregnany to pregnant people and their infants. Ultimately, we expect our participation to inform pateint-centered care for this population and increase implementation of prevention activities and dissemination of findings at a local, state, and national level.