Riverside County, CA has been especially hard hit by the COVID-19 pandemic. As of April 29, 2021, Riverside County has reported 298,366 cases and 4,568 deaths. Unfortunately, COVID-19 has disproportionately impacted the most vulnerable populations. The COVID-19 death rate is more than double in the most disadvantaged communities compared to the least disadvantaged communities (269/100,000 vs 128/100,000). In addition, the Hispanic/Latinx, Black/African American, and Native Hawaiian/Pacific Islander populations have experienced the highest COVID-19 case and death rates. Through multi-sectoral community driven partnership, Riverside County aims to address COVID-19 health disparities by supporting efforts to build sustainable infrastructure and advance health equity for underserved populations.