Denver Department of Public Health & Environment's project name: OD2A: Denver - The Denver Department of Public Health and Environment (DDPHE) is a government agency dedicated to promoting and safeguarding the health of Denver communities. In recent years, Denver has experienced a surge in overdose-related deaths, with 225 deaths recorded in 2019 and nearly 400 in 2020, most of which are attributed to opioids and synthetic opioids like fentanyl, as well as stimulants like methamphetamine. To address this growing concern, DDPHE is seeking funding through the Overdose Data to Action: Local (OD2A:Local) grant to expand its overdose prevention efforts in Denver. The OD2A:Denver project (OD2A:Denver hereinafter) aims to expand harm reduction work, linkage to care services, stigma reduction efforts, and drug testing capacities, as well as foster collaboration among healthcare providers to address the current challenges of overdose in Denver communities. Moreover, OD2A:Denver also prioritizes increasing data surveillance work and community engagement (e.g., with people who use drugs ) in overdose prevention and management strategies. Primary collaborators of the project include community partners, healthcare systems, drug testing laboratories, and other stakeholders. Using evidence-based assessments, DDPHE will identify groups and neighborhoods disproportionately affected by overdose and prioritize previously underserved populations to achieve health equity. The ultimate goal of OD2A:Denver is to reduce the number of overdose incidents in Denver by enhancing access to care, reducing stigma, and increasing collaboration among healthcare providers. Through its comprehensive approach, OD2A:Denver seeks to make a positive impact on the health and wellbeing of Denver communities.