Monday, September 15, 2025 9/15/2025

Institutional Career Development Core

Award Number: KL2TR001862
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SOCIAL SERVICES
PERIOD OF PERFORMANCE START DATE: 07/01/2016
PERIOD OF PERFORMANCE END DATE: 05/31/2026

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Institutional Career Development Core - The KL2 Mentored Clinical Scholars Program attracts highly talented junior faculty across multiple disciplines from across Yale University who will pursue careers in T1-T4 translational research. This Program has been extremely successful, attracting 151 Scholars who have authored >5200 publications, have been PIs on 258 NIH grants, and have received a total of $557 million in grant funding. Remarkably, 99% of our KL2 Scholars have attained positions in academia, industry or public health conducting, and often with leadership responsibilities for, clinical and translational research. We aim to build on this success by providing Scholars with individualized, competency-based training in translational research that prepares them to contribute to the learning healthcare system, to advance personalized health, and to improve health outcomes for all. This preparation includes training in clinical trials, big data, machine learning, bioinformatics, multidisciplinary translational research, team science, implementation science, and community-based participatory research. It also introduces them to regulatory issues, bioethics, Good Clinical Practices, and factors that drive rigor, transparency, and replicability. The KL2 promotes the development of relevant competencies among the Scholars by providing: 1) opportunities to work successfully in complex multidisciplinary research teams, 2) access to mentorship by senior mentors and recent Clinical Scholars, 3) externships in industry, public health and regulatory agencies, and 4) intensive training in grant-writing and in multidisciplinary team science. To oversee these highly motivated junior investigators, we have an educational leadership team of three outstanding investigator mentors and an expert in evaluating and dynamically reshaping medical education programs. We expanded our logic model to implement social network analyses to track the activities of the Scholars, and we will expand the curriculum to include a new course. That course will mix Scholars and TL1 trainees who will work in teams as they get formal training and peer mentoring in a variety of areas such as big data/machine learning, translational science, community-engaged research, and running a research laboratory. With these additions to an already strong curriculum, we believe that the Yale Mentored Clinical Scholars Program will be ideally positioned to train the next generation of leaders in T1-T4 translational research who will transform healthcare in ways that alleviate the burden of disease and improve health in the US and around the world. The Specific Aims of the KL2 are: Aim 1: The Yale Mentored Clinical Scholars Program: To provide a program comprised of a mentored research experience, coursework, and seminars that are intended to promote the emergence of scientific independence and the career development of talented young T1-T4 translational scientist Scholars. Aim 2: The Yale Masters in Health Science Program: To provide those M.D. Scholars who do not possess an advanced research degree with additional coursework and scholarly activities to qualify for a Masters in Health Science to augment their scientific preparation for a research career.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,318,718 )
2025	2025	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	10	7/31/2025	NON-COMPETING CONTINUATION	$1,318,718
														Subtotal = $1,318,718

Issue Date FY: 2024 ( Subtotal = $1,318,718 )
2024	2024	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	9	5/16/2024	NON-COMPETING CONTINUATION	$1,318,718
														Subtotal = $1,318,718

Issue Date FY: 2023 ( Subtotal = $1,318,718 )
2023	2023	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	8	6/29/2023	NON-COMPETING CONTINUATION	$1,318,718
														Subtotal = $1,318,718

Issue Date FY: 2022 ( Subtotal = $707,623 )
2022	2022	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	003	7	6/9/2022	NON-COMPETING CONTINUATION	$1,318,718
2022	2022	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	004	7	7/18/2022	NON-COMPETING CONTINUATION	-$611,095
2022	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	002	6	12/14/2021	COMPETING CONTINUATION	$0
2022	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	001	6	11/7/2021	COMPETING CONTINUATION	$611,094
2022	2020	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	5	11/7/2021	NON-COMPETING CONTINUATION	-$611,094
														Subtotal = $707,623

Issue Date FY: 2021 ( Subtotal = $1,318,718 )
2021	2021	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	6	6/1/2021	COMPETING CONTINUATION	$1,318,718
														Subtotal = $1,318,718

Issue Date FY: 2020 ( Subtotal = $1,244,082 )
2020	2020	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	5	5/30/2020	NON-COMPETING CONTINUATION	$1,244,082
														Subtotal = $1,244,082

Issue Date FY: 2019 ( Subtotal = $1,244,082 )
2019	2019	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	4	7/12/2019	NON-COMPETING CONTINUATION	$1,244,082
														Subtotal = $1,244,082

Issue Date FY: 2018 ( Subtotal = $1,244,082 )
2018	2018	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	3	8/6/2018	NON-COMPETING CONTINUATION	$1,244,082
														Subtotal = $1,244,082

Issue Date FY: 2017 ( Subtotal = $1,244,082 )
2017	2017	YALE UNIVERSITY	105 WALL ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	2	6/16/2017	NON-COMPETING CONTINUATION	$1,244,082
														Subtotal = $1,244,082

Issue Date FY: 2016 ( Subtotal = $1,244,082 )
2016	2016	YALE UNIVERSITY	47 College Street	NEW HAVEN	CT	06520	SOUTH CENTRAL CT	USA	National Center for Advancing Translational Sciences	000	1	7/1/2016	NEW	$1,244,082
														Subtotal = $1,244,082

Grand Total All Awards = $12,202,905

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Institutional Career Development Core

Award Number: KL2TR001862

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SOCIAL SERVICES

PERIOD OF PERFORMANCE START DATE: 07/01/2016

PERIOD OF PERFORMANCE END DATE: 05/31/2026

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