Project Abstract
Each year in the U.S., millions of Spanish-speaking Hispanics experience negative consequences from
harmful alcohol use. Hispanics suffer from alcohol use disorder (AUD) and alcohol-related liver disease at rates
similar to non-Hispanic Whites. However, Hispanics with AUD are less likely to receive treatment than non-
Hispanic Whites. Hispanics also face greater socioeconomic, cultural, and linguistic barriers to treatment for AUD
than non-Hispanic Whites. These barriers include limited access to Spanish-speaking providers and culturally
adapted evidence-based treatments. Computerized treatments and mobile technology have significant potential
to increase access to evidence-based treatments in a cost-effective manner for Spanish speakers. A culturally
adapted computerized treatment for Spanish-speaking Hispanics with substance use disorders has
demonstrated efficacy at reducing rates of alcohol and drug use in a randomized clinical trial (Computer-Based
Training for Cognitive Behavioral Therapy; Spanish CBT4CBT). Several other clinical trials have supported
the efficacy and cost-effectiveness of English versions of CBT4CBT. Rapid, mobile delivery of CBT skills would
facilitate treatment feasibility during risky periods for drinking in daily life (e.g. weekend evenings). But, CBT4CBT
modules each require 35-40 minutes of sustained attention to complete and cannot be used quickly during high-
risk drinking periods. This project proposes to develop a concentrated mobile version of Spanish
CBT4CBT to rapidly deliver treatment content on high-risk drinking days: Aim 1) Identify Spanish
CBT4CBT module topics associated with greater reductions in daily alcohol use and psychiatric symptoms. Aim
2) Develop a concentrated version of Spanish CBT4CBT consisting of a subset of content from the current
modules. Aim 3) Test the feasibility and acceptability of using smartphones to deliver a concentrated version of
Spanish CBT4CBT on high-risk drinking days.
To complete these aims, my career development plan includes mentored training in the following domains:
1) conducting clinical trials of treatments for AUD; 2) designing culturally adapted treatments for Hispanics; 3)
delivering treatment components through smartphones; 4) using mixed methods to explore stakeholders’
perspectives on treatments for AUD; 5) fostering professional development through grant writing, publishing,
leadership, and networking. This award will provide me with hands-on experience in ongoing clinical trials of
computerized treatments for Spanish speakers with AUD. I will participate in NIH training programs on digital
technologies, minority health, and professional development, including the MOSAIC UE5 leadership forums. I
will complete Yale University courses on clinical trial methods, qualitative research, and grant writing. These
activities will build on my prior expertise with using mobile technology and advanced statistics to study the
temporal dynamics of motivation for drinking and social processes. This award will support my transition to an
independent research career developing mobile treatments for Hispanics to target drinking in real-time.