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Prevalence and Impact of Frailty among Dialysis Patients

Award Number: K24DK085153
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

Group Awards By Issue Date FY or Funding FY:

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PROJECT SUMMARY/ABSTRACT I am applying to renew my Mid-career Investigator Award in Patient Oriented Research (K24) in order to support my research and mentoring efforts. I am fully committed to patient oriented research and to training the next generation of researchers in nephrology research. I have developed a research program studying physical functioning in patients on dialysis, characterizing their limitations, studying the pathophysiology, and evaluating interventions to improve functioning. While my previous and currently funded work aims to assess frailty and its evolution among patients on dialysis, I am convinced that physical function and frailty could add important information to inform clinical care at other points along the spectrum of CKD. In particular, I plan to expand my focus to the transitions of care from non-dialysis requiring CKD to ESRD and from dialysis to transplantation. Aims are to examine associations of functional status during CKD with outcomes during ESRD in a national cohort of veterans and to measure physical performance in a cohort of kidney transplant candidates to determine the extent to which post-transplant outcomes are related to physical performance and frailty during pre-transplant evaluation. I have a strong track record of mentoring, and I work within a rich, supportive, and collegial environment at UCSF and in the Division of Nephrology. Continued K24 funding will permit me to continue to focus more of my time on research and mentoring and less on clinical and administrative work.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$169,295 )
2024	2021	HENNEPIN HEALTHCARE RESEARCH INSTITUTE	701 PARK AVE	MINNEAPOLIS	MN	55415	HENNEPIN	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	11	1/8/2024	NON-COMPETING CONTINUATION	-$149,045
2024	2020	HENNEPIN HEALTHCARE RESEARCH INSTITUTE	701 PARK AVE	MINNEAPOLIS	MN	55415	HENNEPIN	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	10	1/8/2024	NON-COMPETING CONTINUATION	-$20,250
														Subtotal = -$169,295

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	7	5/16/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = -$2,319 )
2022	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	7	6/29/2022	NON-COMPETING CONTINUATION	-$2,319
2022	2017	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	6	6/29/2022	COMPETING CONTINUATION	$0
														Subtotal = -$2,319

Issue Date FY: 2021 ( Subtotal = $149,045 )
2021	2021	HENNEPIN HEALTHCARE RESEARCH INSTITUTE	701 PARK AVE	MINNEAPOLIS	MN	55415	HENNEPIN	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	11	6/7/2021	NON-COMPETING CONTINUATION	$149,045
														Subtotal = $149,045

Issue Date FY: 2020 ( Subtotal = $148,786 )
2020	2020	HENNEPIN HEALTHCARE RESEARCH INSTITUTE	701 PARK AVE	MINNEAPOLIS	MN	55415	HENNEPIN	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	10	6/4/2020	NON-COMPETING CONTINUATION	$148,786
														Subtotal = $148,786

Issue Date FY: 2019 ( Subtotal = $148,584 )
2019	2019	HENNEPIN HEALTHCARE RESEARCH INSTITUTE	701 PARK AVE	MINNEAPOLIS	MN	55415	HENNEPIN	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	9	5/6/2019	NON-COMPETING CONTINUATION	$148,584
2019	2018	HENNEPIN HEALTHCARE RESEARCH INSTITUTE	701 PARK AVE	MINNEAPOLIS	MN	55415	HENNEPIN	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	8	3/28/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$147,802
2019	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	7	3/28/2019	NON-COMPETING CONTINUATION	-$147,802
														Subtotal = $148,584

Issue Date FY: 2018 ( Subtotal = $180,139 )
2018	2018	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	7	5/30/2018	NON-COMPETING CONTINUATION	$180,139
														Subtotal = $180,139

Issue Date FY: 2017 ( Subtotal = $176,494 )
2017	2017	UNIVERSITY OF CALIFORNIA, SAN FRANCISCO	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	6	6/19/2017	COMPETING CONTINUATION	$181,142
2017	2014	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 420	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	5	1/5/2017	NON-COMPETING CONTINUATION	-$4,648
														Subtotal = $176,494

Issue Date FY: 2014 ( Subtotal = $131,226 )
2014	2014	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	5	9/8/2014	NON-COMPETING CONTINUATION	$131,226
														Subtotal = $131,226

Issue Date FY: 2013 ( Subtotal = $131,231 )
2013	2013	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	4	8/26/2013	NON-COMPETING CONTINUATION	$131,231
														Subtotal = $131,231

Issue Date FY: 2012 ( Subtotal = $131,233 )
2012	2012	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	3	8/24/2012	NON-COMPETING CONTINUATION	$131,233
														Subtotal = $131,233

Issue Date FY: 2011 ( Subtotal = $132,106 )
2011	2011	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	2	8/31/2011	NON-COMPETING CONTINUATION	$132,106
														Subtotal = $132,106

Issue Date FY: 2010 ( Subtotal = $129,808 )
2010	2010	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	9/7/2010	NEW	$129,808
														Subtotal = $129,808

Grand Total All Awards = $1,287,039

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Prevalence and Impact of Frailty among Dialysis Patients

Award Number: K24DK085153

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

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