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Mentoring the next generation of researchers at the intersection of opioid use disorder and chronic pain

Award Number: K24DA056837
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 04/01/2023
PERIOD OF PERFORMANCE END DATE: 03/31/2028

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Mentoring the next generation of researchers at the intersection of opioid use disorder and chronic pain - My overall goal is to improve the health and well-being of individuals with comorbid opioid misuse/opioid use disorder (OUD) and chronic pain across varied settings and populations. Research on the management of comorbid opioid misuse/OUD and chronic pain is being outpaced by the clinical need across populations and settings. Additionally, there is no well-worn training pathway to conduct research in this area, few mid-career and senior investigators have the expertise to mentor early-career investigators in this space, and the need for mentoring to grow the workforce is enormous. I am a physician and PhD-trained behavioral scientist who treats individuals with opioid misuse/OUD and chronic pain. I have a consistent track record of NIH-funded research and productive mentoring at the intersection of these conditions across populations and settings including HIV, cancer, and primary care, and am at an institution with exceptional resources to support trainees. This K24 mid-career investigator award will allow me to grow the workforce at the intersection of opioid misuse/OUD and chronic pain by 1) expanding my capacity to mentor PhD students, postdoctoral scholars, and faculty from a variety of disciplines in research on comorbid opioid misuse/OUD and chronic pain; 2) Become a leader in implementation science approaches to studying treatment of comorbid opioid misuse/OUD and chronic pain, including hybrid trials; and 3) Develop the skills needed to systematically incorporate health policy considerations and methods throughout my work. I have assembled a team of advisors with whom I have created a comprehensive career development plan including didactic coursework, experiential learning, and conference attendance that will allow me to excel at achieving these goals. Additionally, this K24 proposes a new research project that leverages existing Delphi-based preliminary data to 1) Develop an implementation strategy bundle to promote the adoption and application of evidence-informed approaches (EIAs) to managing opioid misuse/OUD and metastatic cancer-related pain, and 2) Conduct a hybrid type 2 pilot trial of the approaches and implementation strategy bundle. Findings from this study will lead to a hybrid type 2 randomized trial of the implementation strategy bundle and ultimately improved care for patients with opioid misuse/OUD and metastatic cancer. This and other NIH- funded studies in my portfolio will provide mentees ample opportunity to propose mentored research projects. This mentored research experience, combined with a program of tailored career development opportunities, will develop a new cadre of independent investigators at the intersection of opioid misuse/OUD and chronic pain.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $192,683 )
2026	2026	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Drug Use and Addiction Research Programs	001	4	1/30/2026	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$192,683
2026	2025	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Drug Use and Addiction Research Programs	000	3	1/30/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $192,683

Issue Date FY: 2025 ( Subtotal = $192,671 )
2025	2025	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Drug Use and Addiction Research Programs	000	3	4/25/2025	NON-COMPETING CONTINUATION	$192,671
														Subtotal = $192,671

Issue Date FY: 2024 ( Subtotal = $192,656 )
2024	2024	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Drug Use and Addiction Research Programs	000	2	2/29/2024	NON-COMPETING CONTINUATION	$192,656
														Subtotal = $192,656

Issue Date FY: 2023 ( Subtotal = $192,594 )
2023	2023	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Drug Use and Addiction Research Programs	000	1	3/27/2023	NEW	$192,594
														Subtotal = $192,594

Grand Total All Awards = $770,604

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Mentoring the next generation of researchers at the intersection of opioid use disorder and chronic pain

Award Number: K24DA056837

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 04/01/2023

PERIOD OF PERFORMANCE END DATE: 03/31/2028

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