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Technology-Enhanced Adherence to Medication intervention for youth with Type 2 Diabetes (TEAM-T2D)

Award Number: K23DK146162
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 04/01/2026
PERIOD OF PERFORMANCE END DATE: 03/31/2031

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Technology-Enhanced Adherence to Medication intervention for youth with Type 2 Diabetes (TEAM-T2D) - PROJECT SUMMARY/ABSTRACT Pediatric type 2 diabetes (T2D) is rapidly increasing, with U.S. cases projected to quadruple by 2050. Youth- onset T2D follows a more aggressive disease course than adult-onset, increasing the risk for early microvascular complications. Medication adherence is critical for maintaining glycemic control, yet up to 70% of youth with T2D are nonadherent to their prescribed regimen. Despite the urgent need for adherence interventions, no evidence- based strategies exist for youth with T2D, leaving a critical gap in care. Technology-enhanced adherence interventions, including mobile monitoring devices, tailored text message feedback, and telehealth, have demonstrated efficacy in type 1 diabetes and adult T2D but remain untested in pediatric T2D. This K23 proposal aims to develop and evaluate TEAM-T2D (Technology-Enhanced Adherence to Medication intervention for youth Type 2 Diabetes), an intervention co-designed with key stakeholders (youth with T2D, parents, and healthcare providers) to address adherence barriers of youth with T2D. In Aim 1, the PI and the mentorship team will employ a patient-engaged participatory research approach to develop and refine the TEAM-T2D intervention to ensure feasibility and acceptability. Aim 2 will involve conducting a pilot randomized controlled trial (RCT) to evaluate the feasibility and acceptability of TEAM-T2D intervention in a sample of 40 youth with T2D. Feasibility and acceptability will be assessed through validated surveys and qualitative interviews. Medication adherence will be monitored electronically and serve as a secondary outcome. This K23 award will provide the PI with training in 1) patient-engaged research methods, 2) mixed methodologies for intervention development, 3) advanced training in clinical trial design and conduct, and 4) leadership and management expertise to conduct multidisciplinary research in pediatric diabetes care. Successful completion of this project will yield critical pilot data to inform a future R01-funded Type 2 hybrid implementation/ effectiveness trial, positioning the PI as a leader in adherence intervention research for youth with T2D.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $177,877 )
2026	2026	REGENTS OF THE UNIVERSITY OF MINNESOTA	2221 UNIVERSITY AVE SE STE 100	MINNEAPOLIS	MN	55414	HENNEPIN	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	3/19/2026	NEW	$177,877
														Subtotal = $177,877

Grand Total All Awards = $177,877

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Technology-Enhanced Adherence to Medication intervention for youth with Type 2 Diabetes (TEAM-T2D)

Award Number: K23DK146162

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 04/01/2026

PERIOD OF PERFORMANCE END DATE: 03/31/2031

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