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Integrating Behavioral Pain Management to Improve Physical Activity in Family-based Behavioral Treatment for Pediatric Obesity

Award Number: K23DK143352
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 05/01/2026
PERIOD OF PERFORMANCE END DATE: 02/28/2031

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Integrating Behavioral Pain Management to Improve Physical Activity in Family-based Behavioral Treatment for Pediatric Obesity - PROJECT SUMMARY/ABSTRACT Chronic pain is prevalent in youth with obesity and confers risk for declining physical function and quality of life. Left unaddressed, chronic pain often persists into adulthood and is associated with staggering costs to individuals and to society. Despite evidence that chronic pain attenuates responsiveness to weight management intervention, there is a lack of safe and effective behavioral interventions for pain management in pediatric patients with obesity. The long-term objective of this work is to improve obesity treatment outcomes by optimizing strategies to decrease pain and improve physical activity in youth with co-occurring obesity and chronic pain (CPO). Guided by the ORBIT Model of Behavioral Intervention Development, the goal of this proposal is to develop, refine, and pilot test an adjunctive behavioral pain management intervention that targets physical activity in youth with CPO who are participating in family-based behavioral treatment (FBBT) for pediatric obesity (i.e., IMPACT-FBBT). In Aim 1, the PI and his mentorship team will identify biological, psychological, and social factors that are predictive of moderate-to-vigorous physical activity (MVPA) and sedentary behavior in youth with CPO (N=20). In Aim 2a, these data will be used to inform the initial development of the IMPACT-FBBT intervention, which will be based on a highly successful behavioral treatment program that has been implemented in youth with chronic widespread pain (i.e., FIT Teens) but modified with input from youth with CPO and their families (n=10) and multidisciplinary experts who treat youth with CPO (n=5). Then, in Aim 2b, the investigative team will refine IMPACT-FBBT through sequential testing with youth with CPO (n=6 minimum) and structured participant feedback. Intervention refinement will continue until we achieve feasibility and acceptability ratings that exceed >80% or until N=12 youth with CPO complete the intervention and provide feedback. In Aim 3, we will pilot test the refined IMPACT-FBBT intervention with N=30 adolescents with CPO and assess recruitment, retention, and dose received. This information will be used to inform the future fully powered efficacy trial. Identifying strategies to reduce pain and improve physical activity in the context of weight management treatment has the potential to prevent the long-term health consequences of CPO, ultimately leading to a more cost-effective approach to pediatric obesity management. By leveraging the resources of a strong mentorship team and nationally renowned pediatric obesity treatment center, this K23 will provide the PI with skills in (1) pediatric obesity intervention and body composition assessment; (2) physical activity measurement; (3) development and refinement of behavioral interventions; and (4) conduct of clinical trials. The proposed research and training plan will occur within a rich academic environment supported by a multidisciplinary team of highly successful expert researchers and clinicians. This will support the PI’s transition to independence as a pediatric chronic pain intervention researcher with the skills and expertise needed to develop and implement evidence- based behavioral interventions for patients with CPO.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $171,069 )
2026	2026	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	5/1/2026	NEW	$171,069
2026	2026	UNIVERSITY OF KANSAS MEDICAL CENTER RESEARCH INSTITUTE, INC.	3901 RAINBOW BLVD	KANSAS CITY	KS	66160	WYANDOTTE	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	1	5/8/2026	NEW	$0
														Subtotal = $171,069

Grand Total All Awards = $171,069

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Integrating Behavioral Pain Management to Improve Physical Activity in Family-based Behavioral Treatment for Pediatric Obesity

Award Number: K23DK143352

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 05/01/2026

PERIOD OF PERFORMANCE END DATE: 02/28/2031

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