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A Mobile Mindfulness-Based Intervention for Unhealthy Alcohol Use in People with Anxiety

Award Number: K23AA033108
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/09/2026
PERIOD OF PERFORMANCE END DATE: 06/30/2031

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A Mobile Mindfulness-Based Intervention for Unhealthy Alcohol Use in People with Anxiety - PROJECT SUMMARY/ABSTRACT This Mentored Patient-Oriented Research Career Development application (K23) will provide protected time for Dr. Natalia Van Doren to strengthen her trajectory as an independent researcher at the University of California, San Francisco (UCSF) and the Kaiser Permanente Northern California (KPNC) Division of Research. Her career goal is to become an expert in developing and testing digital health interventions to address the spectrum of unhealthy alcohol use in people with chronic mental health comorbidities, an area of critical public health importance aligned with NIAAA Strategic Plan, Goal 4. Building on her existing training in clinical psychology and health services research, the integrated training and research plans proposed in this application will provide Dr. Van Doren with advanced training in several critical areas needed to enhance her program of research. Under the mentorship of leaders in alcohol treatment and digital health, training includes: (1) tailoring evidence-based alcohol interventions for mobile platforms (Dr. Maureen Walton; Dr. Sarah Bowen), (2) qualitative methods for treatment research (Dr. Karen Osilla), (3) conducting randomized clinical trials (RCTs) (Dr. Derek Satre; Dr. Stacy Sterling), (4) advanced longitudinal data analysis (Dr. Nicholas Jacobson). These training objectives will be achieved through a combination of didactic and applied activities and through the application of these skills in a Stage 1 behavioral treatment development trial involving the adaptation and initial pilot testing of a novel mindfulness-based ecological momentary intervention (MEMI) targeting unhealthy alcohol use in people with anxiety. Target areas for learning in each training domain are directly linked to the specific aims of this research study, which include (1) iteratively tailoring and optimizing the MEMI to address unhealthy alcohol use in people with anxiety; (2) conducting a pilot RCT to (2a) assess feasibility/acceptability and (2b) generate initial effect size estimates of intervention efficacy compared to a self- monitoring placebo, in preparation for a future R01 trial; and (3) using intensively collected ecological momentary assessments (EMA) to examine within-person mechanisms of change, aligned with the NIH Science of Behavior Change (SOBC) framework. UCSF and KPNC provide ideal environments for the attainment of these training and research objectives, including an established digital health ecosystem within KPNC, seminars and courses in designated training areas, and a highly active Clinical and Translational Science Center at UCSF with a wide array of resources for career development and training. This K23 Award will provide Dr. Van Doren with a repertoire of advanced skills designed to complement her prior training and to provide an essential bridge between her prior experience and her career goal to conduct an active program of patient-oriented research as an independent scientist, toward the ultimate goal of reducing the public health burden of unhealthy alcohol use.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $203,036 )
2026	2026	REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, THE	1855 FOLSOM ST STE 425	SAN FRANCISCO	CA	94103	SAN FRANCISCO	USA	Alcohol Research Programs	000	1	7/9/2026	NEW	$203,036
														Subtotal = $203,036

Grand Total All Awards = $203,036

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A Mobile Mindfulness-Based Intervention for Unhealthy Alcohol Use in People with Anxiety

Award Number: K23AA033108

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/09/2026

PERIOD OF PERFORMANCE END DATE: 06/30/2031

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