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Social Epidemiology of COVID-19

Award Number: K08AI139361
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 03/06/2019
PERIOD OF PERFORMANCE END DATE: 02/28/2023

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Social Epidemiology of COVID-19 - Modified Project Summary/Abstract Section Dr. Richardson is an infectious disease physician with doctoral training in anthropology who is establishing himself as a young investigator in clinical and social scientific research of emerging infectious diseases such as Ebola virus and SARS-CoV-2. This K08 award will provide Dr. Richardson with the support necessary to accomplish the following goals: (1) to conduct clinical and social scientific investigations of COVID-19 in sub-Saharan Africa; (2) to learn to design more effective containment strategies for emerging infectious diseases by integrating rigorous ethnographic and epidemiological evidence; (3) to become an expert in the social epidemiology of emerging infectious diseases in low-income settings; and (4) to develop an independent clinical research career. Dr. Richardson has a strong background in clinical infectious diseases and anthropology. This career development award will enable him to address several remaining gaps in the training specific to his career goals. Specifically, he seeks advanced training in (1) epidemiology and (2) biostatistics and will accomplish through coursework at the Harvard School of Public Health. To further achieve his training goals, Dr. Richardson has assembled a mentoring team comprised of: Primary mentors: Dr. Paul Farmer, who conducts anthropological global health research, and Dr. Ichiro Kawachi, a world renown expert in social epidemiology; Advisers: Dr. Megan Murray, an expert in infectious disease transmission dynamics, Dr. Mosoka Fallah, Director of the National Public Health Institute of Liberia (NPHIL), and Dr. Phyllis Kanki, who has decades of virology experience in West Africa. The novel coronavirus which causes COVID-19 was first reported in Hubei Province, China in December 2019. In the ensuing 4 months, the outbreak spread to nearly every country in the world. The arrack rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suggests that 50-60% or more of the global population may become infected as it assumed that nearly all are immunologically naïve. Despite the rapid development of real-time reverse transcription polymerase chain reaction (RT-PCR) testing for detection of virus in infected patients, many questions remain about SARS-CoV-2 seroprevalence and transmission dynamics. This is because many infected cases remain asymptomatic albeit contagious. Moreover, many symptomatic infections go undetected on account of the slow scale-up of RT-PCR testing. These dynamics have their greatest ramifications for healthcare settings, since healthcare workers are one of the few populations that cannot practice social distancing. It is important to know the attack rate in these groups in order to improve infection prevention and control and decrease nosocomial transmission of the virus. This becomes more important in resource-constrained settings, where optimal PPE stocks are difficult to come by. Novel strategies for healthcare interactions may need to be developed in such cases. Accordingly, this study will determine the proportion of asymptomatic SARS-CoV-2 infection and the attack rate amongst African healthcare workers in various settings through serosurveillance (Aim 1). It will also evaluate the role of social and epidemiologic factors in the acquisition of SARS-CoV-2 infection (Aim 2). This research will form the basis for a longitudinal study of the impact of herd immunity and SARS-CoV-2 vaccine rollouts on future pandemic waves.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$22,139 )
2024	2022	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	4	1/16/2024	NON-COMPETING CONTINUATION	-$22,139
														Subtotal = -$22,139

Issue Date FY: 2022 ( Subtotal = $187,920 )
2022	2022	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	4	3/2/2022	NON-COMPETING CONTINUATION	$187,920
														Subtotal = $187,920

Issue Date FY: 2021 ( Subtotal = $187,920 )
2021	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	3	3/3/2021	NON-COMPETING CONTINUATION	$187,920
														Subtotal = $187,920

Issue Date FY: 2020 ( Subtotal = $187,920 )
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	003	2	9/16/2020	NON-COMPETING CONTINUATION	$0
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	002	2	9/15/2020	NON-COMPETING CONTINUATION	$0
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	004	2	9/18/2020	NON-COMPETING CONTINUATION	$0
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	001	2	7/31/2020	NON-COMPETING CONTINUATION	$0
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	2	2/14/2020	NON-COMPETING CONTINUATION	$187,920
														Subtotal = $187,920

Issue Date FY: 2019 ( Subtotal = $187,477 )
2019	2019	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Allergy and Infectious Diseases Research	000	1	3/6/2019	NEW	$187,477
														Subtotal = $187,477

Grand Total All Awards = $729,098

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Social Epidemiology of COVID-19

Award Number: K08AI139361

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 03/06/2019

PERIOD OF PERFORMANCE END DATE: 02/28/2023

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