Friday, July 18, 2025 7/18/2025

The Functional Anatomy of Adolescent ADHD: Defining Markers of Recovery

Award Number: K01MH082123
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/19/2008
PERIOD OF PERFORMANCE END DATE: 01/31/2014

Group Awards By:

View Award Description

The Functional Anatomy of Adolescent ADHD: Defining Markers of Recovery - DESCRIPTION (provided by applicant): This is a revised K01 application to facilitate the candidate's development into a successful applied neuroscience researcher investigating the neurobiological bases of cognitive impairment in neurodevelopmental disorders, with a special emphasis on Attention Deficit Hyperactivity Disorder (ADHD). The candidate is an experimental psychologist, well versed in functional magnetic resonance imaging (fMRI), whose previous published work examines the functional-anatomic correlates of cognitive control across the adult lifespan. The candidate is proposing to obtain further training in developmental neuroscience, clinical approaches to developmental disability and neurodevelopmental disorders, and in multispectral brain imaging from a distinguished panel of mentors representing multiple disciples. The aim of the mentor project is to use diffusion tensor imaging (DTI) and fMRI to examine the structural and functional-anatomic correlates of cognitive control in adolescents who have shown varying levels of recovery since an initial diagnosis of ADHD-Combined type in childhood. Cognitive control will be examined with a battery of tasks that index several aspects of controlled processing. FMRI studies will also be conducted that will, for the first time in ADHD, examine sustained changes in brain activity (independent of transient trial-related effects) that associate with higher order supervisory control functions (i.e., "control states" or "task sets") that appear to be impaired in ADHD. We hypothesize that different levels of cognitive and psychiatric impairment in the clinical group will be accompanied by discernable changes in white-matter structural integrity and brain activation patterns (notably in fronto-striatal-cerebellar circuits) relative to controls. Results from the mentor project will be crucial for developing a neurobehavioral model of dysfunction in ADHD that can inform treatment and remediation of functional status. The importance of doing so is underlined by recent conservative estimates of the prevalence of ADHD in childhood on the order of 3-5% in the US, with persistence rates of 40-70% through adolescence. The training proposed in this application will allow the candidate to obtain unique experience in multidisciplinary collaboration using her background in neuroimaging and cognitive psychology to enable translational research linking basic neuroscience with child psychiatry, neurology, neuropsychology, child development and functional status.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2014 ( Subtotal = $0 )
2014	2012	UNIVERSITY OF PITTSBURGH	123 UNIVERSITY PLACE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Mental Health Research Career/Scientist Development Awards	000	5	4/29/2014	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2012 ( Subtotal = $141,687 )
2012	2012	UNIVERSITY OF PITTSBURGH	123 UNIVERSITY PLACE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Mental Health Research Career/Scientist Development Awards	000	5	6/9/2012	NON-COMPETING CONTINUATION	$141,687
														Subtotal = $141,687

Issue Date FY: 2011 ( Subtotal = $143,171 )
2011	2011	UNIVERSITY OF PITTSBURGH	123 UNIVERSITY PLACE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Mental Health Research Career/Scientist Development Awards	000	4	6/14/2011	NON-COMPETING CONTINUATION	$143,171
														Subtotal = $143,171

Issue Date FY: 2010 ( Subtotal = $140,556 )
2010	2010	UNIVERSITY OF PITTSBURGH	123 UNIVERSITY PLACE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Mental Health Research Grants	000	3	6/7/2010	NON-COMPETING CONTINUATION	$140,556
														Subtotal = $140,556

Issue Date FY: 2009 ( Subtotal = $138,026 )
2009	2009	UNIVERSITY OF PITTSBURGH	123 UNIVERSITY PLACE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Mental Health Research Grants	000	2	7/15/2009	NON-COMPETING CONTINUATION	$138,026
														Subtotal = $138,026

Issue Date FY: 2008 ( Subtotal = $135,592 )
2008	2008	UNIVERSITY OF PITTSBURGH	3017 CATHEDRAL OF LEARNING	PITTSBURGH	PA	15260	ALLEGHENY	USA	Mental Health Research Grants	000	1	9/22/2008	NEW	$135,592
														Subtotal = $135,592

Grand Total All Awards = $699,032

Top

All Categories

About

Search

Reports

Data Submission

Award Information

The Functional Anatomy of Adolescent ADHD: Defining Markers of Recovery

Award Number: K01MH082123

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/19/2008

PERIOD OF PERFORMANCE END DATE: 01/31/2014

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer