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Delineating Sources of Racial, Ethnic, and Socioeconomic Differences in the Diagnosis of Generalized Anxiety Disorder

Award Number: K01MD020122
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/19/2024
PERIOD OF PERFORMANCE END DATE: 04/30/2030

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Delineating Sources of Racial, Ethnic, and Socioeconomic Differences in the Diagnosis of Generalized Anxiety Disorder - This K01 award will launch Dr. Kerry Kinney’s independent research career focused on reducing disparities in the diagnosis and treatment of generalized anxiety disorder (GAD). GAD is the most common anxiety disorder in primary care settings, where the rate of GAD misdiagnosis is estimated at 67-71%. Misdiagnosis can delay treatment, exacerbate chronicity, and increase personal and societal costs. The proposed K01 research leverages large-scale, epidemiologic and electronic health record (EHR) datasets to evaluate two potential contributors to GAD misdiagnosis: 1) longitudinal measurement non-invariance, or indications that GAD’s diagnostic criteria fail to capture the same construct across over time or across various levels of economic hardship, and 2) lack of patient-centered care, which is characterized by collaborative decision-making and respecting patients’ values and context. To accomplish Aim 1, Dr. Kinney will assess for the presence of measurement non-invariance and differential item functioning in GAD symptom criteria over time and whether longitudinal measurement invariance is moderated by economic hardship in epidemiologic datasets. To accomplish Aim 2, Dr. Kinney will employ natural language processing in EHR data to identify language indicative of non-patient-centered care in primary care notes. She will assess how non-patient-centered care relates to individual patient characteristics and GAD diagnosis. Dr. Kinney proposes to build upon her strong foundational training by targeting career development in: 1) advanced quantitative modeling to enhance theoretical models of GAD; 2) the technical biomedical informatics and textual analysis skills necessary to harness EHR data for health disparities research; and 3) grant-writing skills to obtain independent extramural funding. Dr. Kinney has assembled a highly qualified, interdisciplinary team of mentors, collaborators, and consultants to support her in achieving these training aims. Collectively, the proposed mentor (Dr. Matthew Morris), collaborators (Drs. Glenn Gobbel, Mohammed Al-Garadi, David Cole, and Jacquelyn Pennings), and consultants (Drs. Matthew Diemer and Siddharth Pratap) provide the optimal combination of expertise to facilitate the successful completion of the proposed research and training plan and launch Dr. Kinney’s independent research career. The research and training aims will occur in the exceptional, multidisciplinary, resource-rich environment at Vanderbilt University Medical Center. This K01 award will support Dr. Kinney in establishing an independent research program that aims to advance the field’s understanding of GAD and elucidate the mechanisms underlying missed or delayed opportunities to diagnose and treat GAD.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $95,850 )
2026	2026	VANDERBILT UNIVERSITY MEDICAL CENTER	1161 21ST AVE S STE D3300 MCN	NASHVILLE	TN	37232	DAVIDSON	USA	Minority Health and Health Disparities Research	001	3	5/7/2026	NON-COMPETING CONTINUATION	$95,850
2026	2024	VANDERBILT UNIVERSITY MEDICAL CENTER	1161 21ST AVE S STE D3300 MCN	NASHVILLE	TN	37232	DAVIDSON	USA	Minority Health and Health Disparities Research	000	2	4/15/2026	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $95,850

Issue Date FY: 2025 ( Subtotal = $1 )
2025	2024	VANDERBILT UNIVERSITY MEDICAL CENTER	1161 21ST AVE S STE D3300 MCN	NASHVILLE	TN	37232	DAVIDSON	USA	Minority Health and Health Disparities Research	001	2	7/29/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$100,921
2025	2024	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Minority Health and Health Disparities Research	000	1	7/29/2025	NEW	-$100,920
2025	2024	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Minority Health and Health Disparities Research	002	1	9/9/2025	NEW	$0
														Subtotal = $1

Issue Date FY: 2024 ( Subtotal = $100,921 )
2024	2024	VANDERBILT UNIVERSITY	110 21ST AVE S	NASHVILLE	TN	37203	DAVIDSON	USA	Minority Health and Health Disparities Research	000	1	9/19/2024	NEW	$100,921
														Subtotal = $100,921

Grand Total All Awards = $196,772

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Delineating Sources of Racial, Ethnic, and Socioeconomic Differences in the Diagnosis of Generalized Anxiety Disorder

Award Number: K01MD020122

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/19/2024

PERIOD OF PERFORMANCE END DATE: 04/30/2030

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