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Just-in-time adaptive interventions for improving young Latino sexual minority's success in HIV therapy.

Award Number: K01MD013770
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/18/2018
PERIOD OF PERFORMANCE END DATE: 04/30/2024

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Just-in-time adaptive interventions for improving young Latino sexual minority's success in HIV therapy. - Project Summary/ Abstract Candidate: My long-term career goal is to be an independently funded scientist committed to the elimination of HIV/AIDS and substance use care and treatment disparities among Latino sexual minorities. The immediate and overarching goal of this proposal is to become equipped with innovative tools to examine the role of momentary-state substance use and psychosocial factors, and activity spaces, on antiretroviral therapy (ART) adherence among young Latino men who have sex with men (YLMSM) with HIV and gain foundational knowledge in the design of Just-In-Time Adaptive Interventions (JITAI). Career development plan: I require mentored training in 4 areas to reach my research and career objectives: 1) Latino sexual minority health and research issues; 2) clinical care and treatment of HIV and its syndemics; 3) Ecological Momentary Assessment (EMA) and Global Positioning System (GPS) technology; and 4) design of EMI and JITAI. The training and research plan will be guided by a team of experts: Drs. Trepka (HIV care and treatment; human subject research), Muñoz-Laboy (sexual minority health), Devieux (intervention development), and Duncan (EMA; GPS). Environment: Florida International University (FIU) has a distinguished record of HIV and health disparity research and thus provides an intellectually rich environment for the proposed training and research. In addition to extensive physical resources, I will have access and exposure to expert researchers at the Center for Substance Use and HIV/AIDS Research on Latinos in the US and FIU’s Health Disparities Initiative (HDI). Research Project: The proposed study has two primary objectives. First, we will determine the role of momentary-state substance use and psychosocial factors and the activity spaces where ART occurs on ART adherence among YLMSM living with HIV. Second, we will assess the effect of frequent and repeated measures of ART adherence as a potential intervention for YLMSM and explore the acceptability of a related JITAI. To accomplish our objectives, we propose to implement an EMA/GPS study among 75 YLMSM ages 18-34 in Miami, Florida. The proposed innovative study will be the first to assess how daily changes in substance use, psychosocial factors, and activity spaces impact ART adherence. This information is critical to design JITAI that integrate daily patient-level risk data to adapt and deliver intervention components in real- time during patient’s everyday life. The study is significant because it targets a newly designated health disparity population for NIH research (MSM) living in a metropolitan area with the highest HIV diagnosis rate in the nation, thereby supporting the National HIV/AIDS Strategy objectives of reducing HIV disparities in populations at high risk, including Latinos, MSM, and persons living in the Southern US. In addition, the study will provide me with knowledge, expertise, and research findings to launch my independent research career and successfully submit an R-series grant to design, implement and examine the efficacy of a highly innovative and individualized JITAI that will use EMA/GPS technology to adapt to shifting barriers of ART adherence.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$19,938 )
2024	2022	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	5	9/3/2024	NON-COMPETING CONTINUATION	-$19,938
														Subtotal = -$19,938

Issue Date FY: 2022 ( Subtotal = $135,347 )
2022	2022	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	001	5	5/24/2022	NON-COMPETING CONTINUATION	$13,536
2022	2022	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	5	4/5/2022	NON-COMPETING CONTINUATION	$121,811
														Subtotal = $135,347

Issue Date FY: 2021 ( Subtotal = $135,347 )
2021	2021	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	4	3/22/2021	NON-COMPETING CONTINUATION	$135,347
														Subtotal = $135,347

Issue Date FY: 2020 ( Subtotal = $135,347 )
2020	2020	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	3	4/6/2020	NON-COMPETING CONTINUATION	$135,347
														Subtotal = $135,347

Issue Date FY: 2019 ( Subtotal = $126,318 )
2019	2019	FLORIDA INTERNATIONAL UNIVERSITY	11200 S W 8TH ST MARC 430	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	001	2	5/2/2019	NON-COMPETING CONTINUATION	$126,318
2019	2018	FLORIDA INTERNATIONAL UNIVERSITY	11200 S W 8TH ST MARC 430	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	1	5/2/2019	NEW	$0
														Subtotal = $126,318

Issue Date FY: 2018 ( Subtotal = $135,347 )
2018	2018	FLORIDA INTERNATIONAL UNIVERSITY	11200 S W 8TH ST MARC 430	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	1	9/18/2018	NEW	$135,347
														Subtotal = $135,347

Grand Total All Awards = $647,768

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Just-in-time adaptive interventions for improving young Latino sexual minority's success in HIV therapy.

Award Number: K01MD013770

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/18/2018

PERIOD OF PERFORMANCE END DATE: 04/30/2024

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