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Work-related Asthma Risks for Nursing Staff Conducting Cleaning and Disinfection: Translation of Risk-risk Tradeoff Methodology

Award Number: K01HL168014
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 02/15/2024
PERIOD OF PERFORMANCE END DATE: 01/31/2029

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Work-related Asthma Risks for Nursing Staff Conducting Cleaning and Disinfection: Translation of Risk-risk Tradeoff Methodology - PROJECT SUMMARY/ABSTRACT (limit 30 lines of text) Cleaning and disinfection (C&D) activities pose work-related asthma (WRA) risks for nurses. C&D involves an inherent “risk-risk tradeoff”: increased C&D leading to increased WRA risks and simultaneous decreased occupational infection risks. Our preliminary data from a risk-risk tradeoff survey indicate that nurses are generally willing to increase infection risks to maintain lower asthma risks, if they think they think they will recover. Translating these concerns to C&D protocol changes is challenging due to logistical constraints and lack of awareness about asthma risks from C&D. My long-term goal is to advance methodologies for relating tolerable occupational respiratory disease risks to public health policy interventions. Specific training aims are proposed: 1) Develop independent competency in designing behavioral economic surveys for studying risk perceptions and risk tolerances of WRA, 2) Develop independent competency in conducting health policy analyses in intervention contexts with qualitative methods, 3) Apply bioethics and public health policy principles to risk-risk tradeoff methodologies for assessing evaluations of WRA risk and risk perception. These training aims will be accomplished through formal coursework, involvement in the American Thoracic Society, qualitative research and health policy trainings, and assigned readings and discussion with mentors. The University of Arizona is an ideal environment for the proposed training, offering opportunities for training through faculty at the Asthma & Airway Disease Research Center and the Southwest Environmental Health Sciences Center. This training will be applied through 3 specific research aims: 1) Administer a C&D risk-risk tradeoff survey to 1,000 nurses in the state of Arizona to collect data for microbial risk assessments, 2) Understand barriers to C&D policy changes in the workplace, 3) Identify, describe, and assess C&D policy options with health policy analysis. Aim 1 will involve adaption of a current risk-risk tradeoff survey and recruitment of 1,000 registered nurses. These data will be used in a microbial risk assessment to inform the needed frequency and intensity of C&D to achieve acceptable risks. Aim 2 will involve interviews with registered nurses (n=40) and key informant interviews with facilities management, legal and workers’ compensation staff, occupational health specialists, and infection preventionists (n=2-3/group). Aim 3 will involve the use of a policy Delphi method (n=75). Translating risk-risk tradeoff analysis to inform C&D policies will increase the impact of behavioral economics translation in respiratory occupational health research. Understanding barriers to C&D protocol changes and identifying feasible policy change strategies will inform future efforts (NHLBI R01) to quantify acceptable OA and infection risks, including the perspectives of patients, to implement and evaluate C&D policy changes nationally.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $145,000 )
2026	2026	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Lung Diseases Research	000	3	5/27/2026	NON-COMPETING CONTINUATION	$145,000
														Subtotal = $145,000

Issue Date FY: 2025 ( Subtotal = $145,040 )
2025	2025	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Lung Diseases Research	000	2	4/15/2025	NON-COMPETING CONTINUATION	$145,040
														Subtotal = $145,040

Issue Date FY: 2024 ( Subtotal = $145,041 )
2024	2024	UNIVERSITY OF ARIZONA	845 N PARK AVE RM 538	TUCSON	AZ	85721	PIMA	USA	Lung Diseases Research	000	1	2/8/2024	NEW	$145,041
														Subtotal = $145,041

Grand Total All Awards = $435,081

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Work-related Asthma Risks for Nursing Staff Conducting Cleaning and Disinfection: Translation of Risk-risk Tradeoff Methodology

Award Number: K01HL168014

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 02/15/2024

PERIOD OF PERFORMANCE END DATE: 01/31/2029

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