Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Patient Priorities in Lung Transplant: Quality of Life Outcomes to Inform Decision Making

Award Number: K01HL161330
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 02/01/2023
PERIOD OF PERFORMANCE END DATE: 01/31/2028

Group Awards By:

View Award Description

Patient Priorities in Lung Transplant: Quality of Life Outcomes to Inform Decision Making - Project Abstract/Summary As a health services researcher and Assistant Professor at Temple University, my long-term career goal is to become a leader in preference-based, patient-centered outcomes research to inform decision making for patients with end-stage lung disease, specifically about transplantation decisions. Clinical trials have shown that decision aids improve the quality and efficiency of decision making, improve comprehension and decrease decisional conflict. Despite these benefits, few decision aids have addressed the complexity of lung transplant. A critical barrier to the development of decision aids is the inability to inform and communicate to patients and caregivers the impact of transplant on quality of life (QoL). Thus, to address these knowledge gaps and pursue my long-term career goals, I will investigate patient priorities for QoL outcomes in the context of lung transplant decision making to inform the development of a decision aid. Three Specific Aims will accomplish this objective. AIM 1: Describe priorities for QoL outcomes and their impact on decision making among patients (n=30-40) and caregivers (n=30-40) at each phase of lung transplant, and clinicians (n=10-15). AIM 2: Measure QoL, priorities for outcomes, and willingness to trade between quantity and quality of life among a prospective cohort of patients (n=200) and caregivers (n=200) considering lung transplant using health-related quality of life measures, best- worst scaling tasks, and treatment tradeoff exercises. AIM 3: Develop and assess the feasibility and acceptability of a decision aid among patient and caregiver dyads (n=30) considering lung transplant. To accomplish these aims, I propose a mixed method approach. Qualitative methods include semi-structured interviews conducted in cross-sectional samples across transplant phases (Aim 1). Quantitative surveys and the feasibility/acceptability study will be collected among patients with end-stage lung disease just starting to consider transplant, as well as their caregivers (Aims 2 and 3). A prospective cohort will be followed over time to identify differences across phases of decision making (Aim 2). Although I have had a productive start to my career, I require further training to execute these Aims, accomplish these goals and achieve independence as an investigator. Specifically, I have identified four short-term career objectives. I will: 1) lead a community-engaged research effort inclusive of patients, caregivers and clinicians; 2) design and implement qualitative and mixed methods approaches to collect and analyze patient experience data; 3) obtain formal training in theory of decision making, interpersonal health communication and risk communication; and 4) acquire domain expertise to apply these skills in the context of lung transplant. I have designed a career development plan to achieve these objectives that includes mentorship from a highly accomplished group of researchers who are dedicated to my career development and experts in decision making theory, decision aid design, health and risk communication, qualitative and mixed methods, and lung transplant. These mentors have long histories of extramural funding and mentoring. In addition to mentored instruction, I will complete didactic coursework and intensive professional trainings.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $147,878 )
2026	2026	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1805 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Lung Diseases Research	001	4	4/2/2026	NON-COMPETING CONTINUATION	$147,878
2026	2025	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1805 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Lung Diseases Research	000	3	3/19/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $147,878

Issue Date FY: 2025 ( Subtotal = $146,847 )
2025	2025	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1805 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Lung Diseases Research	000	3	1/28/2025	NON-COMPETING CONTINUATION	$146,847
														Subtotal = $146,847

Issue Date FY: 2024 ( Subtotal = $169,641 )
2024	2024	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Lung Diseases Research	000	2	1/23/2024	NON-COMPETING CONTINUATION	$169,641
														Subtotal = $169,641

Issue Date FY: 2023 ( Subtotal = $169,149 )
2023	2023	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Lung Diseases Research	001	1	4/18/2023	NEW	$0
2023	2023	TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	1801 N BROAD ST	PHILADELPHIA	PA	19122	PHILADELPHIA	USA	Lung Diseases Research	000	1	1/24/2023	NEW	$169,149
														Subtotal = $169,149

Grand Total All Awards = $633,515

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Patient Priorities in Lung Transplant: Quality of Life Outcomes to Inform Decision Making

Award Number: K01HL161330

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 02/01/2023

PERIOD OF PERFORMANCE END DATE: 01/31/2028

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer