Saturday, July 5, 2025 7/5/2025

Studying the Laryngeal Mechanisms Underlying Dysphonia in Connected Speech

Award Number: K01DC017751
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 04/01/2019
PERIOD OF PERFORMANCE END DATE: 03/31/2026

Group Awards By:

View Award Description

Studying the Laryngeal Mechanisms Underlying Dysphonia in Connected Speech - Project Summary/Abstract This proposal aims to employ the recent advancement of coupling fiberoptic endoscopes with high-speed videoendoscopy (HSV) systems to obtain HSV recordings during connected speech. The goal is to study vocal mechanisms underlying dysphonia in patients with neurogenic voice disorders. The long-term goal of this line of research is to create clinically applicable quantitative methods for functional measurement of vocal fold vibration in connected speech using innovative laryngeal imaging, an approach that could advance clinical voice assessment and treatment practice. In Aim 1, HSV-based measures of vocal fold kinematics will be developed and the influence of these measures on voice audio-perceptual qualities in the patients will be determined. Image processing techniques will be developed to extract such measures from the HSV data in connected speech. The extracted measures will be given as inputs to the statistical models to determine the source of the differences between the normal controls and the patients for different speech phonetic contexts and words. This aim provides an unbiased HSV-based method to predict voice quality. Developing such HSV-based methodology for functional laryngeal examination in connected speech can enhance clinical voice assessment. In addition, better understanding the influence of phonetic context would lead to optimizing the protocols for functional voice assessment through laryngeal imaging in connected speech. In Aim 2, machine learning approaches will be employed to discover hidden physics and unknown laryngeal mechanisms of voice production in the dysphonic patients. The findings of this project will help make necessary adjustments in biomechanical or physiological characteristics of vocal folds to enhance voice quality in patients with neurogenic voice disorders. Therefore, the outcome of this research will aid clinicians in properly selecting, and developing new treatment strategies (therapeutic, medicinal, or surgical), which are based on the gained knowledge of laryngeal mechanisms of dysphonia. The proposed research is in harmony with multiple priority areas of the NIDCD, described in the 2017-2021 Strategic Plan. Both aims support Priority 3 (improve methods of diagnosis, treatment, and prevention) through developing objective HSV-based measures and predicting the voice quality. Comparing laryngeal mechanisms in normal and disordered voices addresses Priority 1 (deepen our understanding of the normal function of the systems of human communication). Both aims propose to study laryngeal mechanisms in patients with neurogenic and functional voice disorders, which addresses Priority 2 (increase our knowledge about conditions that alter or diminish communication and health).


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Research Related to Deafness and Communication Disorders	000	5	3/12/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $137,795 )
2023	2023	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Research Related to Deafness and Communication Disorders	000	5	3/23/2023	NON-COMPETING CONTINUATION	$137,795
														Subtotal = $137,795

Issue Date FY: 2022 ( Subtotal = $137,795 )
2022	2022	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Research Related to Deafness and Communication Disorders	000	4	4/9/2022	NON-COMPETING CONTINUATION	$137,795
														Subtotal = $137,795

Issue Date FY: 2021 ( Subtotal = $137,795 )
2021	2021	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Research Related to Deafness and Communication Disorders	000	3	3/25/2021	NON-COMPETING CONTINUATION	$137,795
														Subtotal = $137,795

Issue Date FY: 2020 ( Subtotal = $137,795 )
2020	2020	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Research Related to Deafness and Communication Disorders	000	2	3/27/2020	NON-COMPETING CONTINUATION	$137,795
														Subtotal = $137,795

Issue Date FY: 2019 ( Subtotal = $137,795 )
2019	2019	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD RM 2	EAST LANSING	MI	48824	INGHAM	USA	Research Related to Deafness and Communication Disorders	000	1	3/27/2019	NEW	$137,795
														Subtotal = $137,795

Grand Total All Awards = $688,975

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Studying the Laryngeal Mechanisms Underlying Dysphonia in Connected Speech

Award Number: K01DC017751

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 04/01/2019

PERIOD OF PERFORMANCE END DATE: 03/31/2026

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer