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Patient-Engaged Development and Testing of a Technology-Based Intervention to Reduce Prenatal Cannabis Use

Award Number: K01DA064938
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 03/15/2026
PERIOD OF PERFORMANCE END DATE: 02/28/2031

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Patient-Engaged Development and Testing of a Technology-Based Intervention to Reduce Prenatal Cannabis Use - PROJECT SUMMARY/ABSTRACT Cannabis use in pregnancy has become increasingly prevalent since the recreational legalization of cannabis in many jurisdictions across the United States. Evidence supports adverse neonatal outcomes associated with prenatal cannabis exposure, including small size at birth, preterm birth, and admission to the neonatal intensive care unit. Moreover, prior research suggests a relationship between cannabis use and certain maternal outcomes, such as gestational hypertension. Despite poor health outcomes, cannabis use has yet to be adequately addressed in prenatal care. Further, most pregnant patients who use cannabis do not perceive it to be harmful. As such, there exists a critical need for systematic screening and intervention among pregnant patients using cannabis, with a focus on non-treatment-seeking patients. Electronic screening and brief intervention (eSBI) is an evidence-based approach touted for its privacy and effectiveness in identifying and addressing substance use through patient-centered counseling approaches that employ motivational interviewing techniques to change behavior. Research suggests that eSBI is effective in ‘teachable moments’ such as during pregnancy, a life event that often motivates individuals to readily adopt risk-reducing health behaviors. Tailored text messaging, moreover, may serve to extend the effects seen in eSBIs. As such, in alignment with NIDA’s 2022-2026 Strategic Plan Priority Area #2 to develop and test novel harm reduction strategies with the requirement that interventions are informed by the lived experience of the individuals who will benefit from them, this study will develop an eSBI and tailored text messaging intervention to reduce cannabis use in pregnancy by establishing a patient advisor committee. By partnering with patient advisors in a co-investigator capacity to develop intervention components at the design phase, it is expected that intervention acceptability, effectiveness, and sustainability will be enhanced. An open trial will be conducted to beta test the eSBI and tailored text messaging intervention for usability and acceptability, followed by a pilot randomized controlled trial to examine intervention feasibility. Moreover, this K01 application outlines specific training goals to complement research activities and achieve the PI’s long-term objective of becoming an independent investigator. Training goals include: (a) developing competency in patient-engaged research, (b) advancing skills in qualitative research methodology, and (c) gaining proficiency in RCT methodology. The training and research activities described in this application will position the PI for an R01 award to assess the efficacy of the intervention in a fully powered trial, and aid her in developing her program of research as an independent maternal health services researcher focused on addressing substance use.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $183,681 )
2026	2026	MICHIGAN STATE UNIVERSITY	426 AUDITORIUM RD	EAST LANSING	MI	48824	INGHAM	USA	Drug Use and Addiction Research Programs	000	1	3/6/2026	NEW	$183,681
														Subtotal = $183,681

Grand Total All Awards = $183,681

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Patient-Engaged Development and Testing of a Technology-Based Intervention to Reduce Prenatal Cannabis Use

Award Number: K01DA064938

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 03/15/2026

PERIOD OF PERFORMANCE END DATE: 02/28/2031

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