PROJECT ABSTRACT
The overarching goal of this Mentored Research Scientist Career Development Award (K01) is to provide Dr.
Ruschelle Leone with the training and research activities needed to become an independent investigator. Her
program of research will focus on developing and evaluating innovative integrated programs for heavy episodic
drinking, cannabis use, and sexual assault. Research estimates 1 in 5 college women experiences sexual assault.
Alcohol, cannabis, and sexual assault victimization have a reciprocal association; alcohol and cannabis are known
risk factors for sexual assault, and women who experience sexual assault are at an increased risk of developing
alcohol and cannabis use disorders. Although prevention efforts targeting potential perpetrators and bystanders
is critical, these programs have yet to demonstrate reductions in rates of sexual assault victimization or
perpetration. As part of comprehensive sexual assault programming, feminist scholars have called for the use of
risk reduction programs to empower women by increasing a woman's ability to recognize and resist sexual
assault by providing skills to avoid, interpret, and resist sexual assault. However, these programs have yet to
directly target alcohol and cannabis use within an integrated framework. This innovative proposal includes
training activities to ensure that Dr. Leone achieves the following four new career goals: 1) Develop expertise in
reducing alcohol misuse, cannabis use, and sexual assault; 2) Receive training in the development and testing of
integrated interventions for alcohol misuse, cannabis use, and sexual assault victimization; 3) Obtain advanced
training in multilevel and longitudinal data analyses; and 4) Hone skills in grant-writing, responsible conduct of
research, and professional development. The mentorship team includes expert psychologists, physicians, and
public health scientists in the following areas: development of web-based interventions for alcohol and sexual
assault (Gilmore), treatments for alcohol and cannabis use (Gray), social norm interventions for alcohol and
cannabis prevention (Neighbors), sexual assault risk reduction programs (Senn), qualitative methods for
intervention development (Salazar), design and analysis of clinical trials (Hayat), and program implementation
(Self-Brown). Dr. Leone will apply the skills acquired during the training activities to a research project focused
on the development of an integrated program for heavy episodic drinking, cannabis use, and sexual assault risk
reduction. The research project includes mixed-methods research to develop program content, assess the
usability and acceptability with college women who engaging in heavy episodic drinking and cannabis use, and
conduct a feasibility randomized controlled trial. This project will establish feasibility of conducting a larger
randomized clinical trial testing the efficacy of the integrated program. The proposed training and research
activities will prepare Dr. Leone for an independent research career focused on the development and evaluation
innovative integrated programs for heavy episodic drinking, cannabis use, and sexual assault. This project is
directly in line with several NIH priorities and will inform a R-level grant to conduct a randomized clinical trial.