Friday, November 22, 2024
11/22/2024
Sepsis, the body's overwhelming and life-threatening response to infection, is the leading cause of death, and the most expensive condition, in U.S. hospitals. Early detection and treatment of sepsis is critical to public health emergency preparedness and disaster response, as these situations can all lead to infection and sepsis, whether through injury, increased vulnerability or exposure to infection, or direct contact with new infective agents. In order to foster and expedite innovation related to sepsis and the understanding of infection management, Sepsis Alliance conceptualized and initiated Sepsis Innovation Collaborative (SIC), a multi-stakeholder collaborative facilitating cross-sector coordination and collaboration across the various stakeholder sectors involved in infection management and sepsis. Since September 30, 2021, Sepsis Alliance has convened over 85 stakeholder members under the auspices of SIC. These stakeholders represent academic, clinical, industry, patient advocacy, reimbursement, research, and other sectors critical to advancing innovation and care for sepsis and infection management. These SIC convening sought to identify existing gaps in care and determine critical needs in sepsis detection and infection management; establish consensus on directions for new innovations to facilitate progress in the field; and aid U.S. government's identification of priorities in improving sepsis care and advancing innovations to improve outcomes nationally and strengthen health security. In this phase of the project, Sepsis Alliance will continue to foster public-private collaboration through SIC's stakeholder-led working groups to ultimately improve sepsis care and response nationwide. Its three primary objectives are to: 1) improve stakeholder-wide understanding of the sepsis patient/survivor perspective and identify opportunities for patient/survivors to contribute to the development of innovative new tools for identification of infection severity and management of sepsis; improve stakeholders' understanding of and ability to navigate regulatory and payment pathways for novel infection management and sepsis-related diagnostics and treatments; and 3) survey, inventory, and review stakeholder-identified issues and opportunities in the clinical trials of novel infection management and sepsis-related diagnostics and treatments. Written white papers will be included in project outputs to document and share findings and share priority areas for urgent innovation and improvement as defined by stakeholder consensus. The expected outcomes of this project are more patient-centric innovation leading to the development of new tools for identification of infection severity and management of sepsis that will ultimately reduce morbidity and mortality from sepsis and to inform future preparedness and response by identifying best practices and areas for improvement and innovation.
HHS’ Tracking Accountability in Government Grants System (TAGGS) website provides access to detailed descriptions of grants, loans, aggregated direct payments and other types of financial assistance awarded by the HHS Operating Divisions (OPDIVs) and the Office of the Secretary Staff Divisions (STAFFDIVs).
