Success: HCV Cures - This project will implement a HCV treatment program that is focused on achieving a high cure rate. The population to be served are individuals who are HCV positive and who are homeless and have serious mental illness and/or a substance use disorder. Project goals include: Goal 1: Cure persons who have HCV by providing evidence-based treatments. Objective: By the end of grant year 1, cure a minimum of 65 persons who are enrolled in the project from HCV, and a minimum of 105 persons in grant year 2. Goal 2: Test persons who are at high risk for HCV. Objective: In grant year 2, demonstrate that HCV testing was provided to a minimum of 250 persons. Goal 3: Engage effective ways of promoting the completion of HCV treatment. Objective: In grant year 2, demonstrate that a minimum of 105 persons complete the SAMHSA defined minimum course of HCV treatment. Goal 4: Utilize effective means for the identification of potential HCV patients. Objective: In grant year 2, demonstrate that 12.5% or more of persons tested for HCV actually test positive for HCV. Goal 5: Promote effective means for the reduction of HCV reinfection. Objective: In grant year 2, demonstrate that wraparound case management was provided to a minimum of 210 persons, as evidenced by the completion of a comprehensive service plan. We anticipate serving 300 clients in year 1, and over 1,300 clients over the 3-years grant.