Brandywine Counseling & Community Services, Inc. (BCCS) proposes to implement a Portable Clinical Care Project (PCCP) to provide comprehensive and integrated behavioral health, human immunodeficiency virus (HIV) and viral hepatitis testing and treatment, mental health treatment, harm reduction & prevention services, low-barrier substance use disorder (SUD) treatment, care/case management, and basic primary medical care to underserved populations experiencing unsheltered homelessness throughout the state of Delaware. The PCCP's population of focus (POF) is exclusively people experiencing unsheltered homelessness throughout the state of Delaware (the PCCP Catchment Area). The PCCP will utilize a syndemic approach to healthcare delivery - focusing on infectious diseases - and will literally serve the POF "where they are", including outdoor and/or public locations where the POF congregate such as encampments, in parks and under bridges, transit stations (bus and train terminals), and in places not meant for habitation. The PCCP will serve a minimum of 75 unduplicated individuals per project year, for a total of 225 individuals over three years. By embracing a syndemic approach, the recognized key strategy of PCCP implementation is the provision of low-barrier substance use disorder (SUD) treatment; HIV and viral hepatitis testing and treatment; STI testing and treatment; HIV/STI prevention and education, mental health care; and harm reduction services. Goals include, but are not limited to, increasing access to and retention in primary medical and substance use disorder treatment in POF, reduce rates of new infections of HIV, Hepatitis, STI's and reduce and increase rates of treatment in active infections, reduce rates of substance abuse in POF by increasing access to care and focusing on co-occurring disorders, increase peer recovery support services through comprehensive case management focusing on POF's social determinants of health needs, and document and disseminate best practices and "lessons learned".