Centerstone's Screening, Brief Intervention, and Referral to Treatment (C-SBIRT) - Centerstone’s Screening, Brief Intervention, and Referral to Treatment (C-SBIRT) will expand the uptake of the SBIRT model in primary care/pediatric, community health, and school settings in 14 Florida counties, with a focus on screening for underage drinking, opioid use, and other substance use. C-SBIRT will screen an unduplicated 16,000 (i.e., Y1: 1,500; Y2: 3,000; Y3: 5,000; Y4: 4,500; Y5: 2,000) via screening; of those, more than 50% will be youth ages 12-21. C-SBIRT’s focus population is expected to mirror area residents’ (12+) demographics (e.g., 49% male; 51% female, 66% White) and socioeconomics (e.g., 12% experience poverty, 12% lack health insurance). C-SBIRT will serve under-served/resourced subpopulations from among the area’s racial/ethnic and sexual/gender minority communities; Veteran/military populations, including Veteran households with children; and/or systems-involved youth populations. Low perception of risk in using substances (e.g., 50% of 12-17 year olds do not see using cocaine 1 time a month as risky) increases early initiation, risk of misuse, and likelihood of SUD for the focus population; an estimated 95.5% with SUD do not recognize the problem, impacting 570,000+ in the focus population. An estimated 46,810 youth and 550,520 adults will have SUD; of those, 3% of youth and nearly 10% of adults will have AUD and 1% of youth and 2% of adults will have OUD. Nearly 3% of youth and 8% of adults are anticipated to have COD. C-SBIRT will establish Youth and Adult Tracks for integrating SBIRT implementation protocols, including population-specific implementation sites, SBIRT teams, tools, interventions, etc. C-SBIRT’s strategies/interventions include capacity-building efforts (e.g., technology integration, annual assessment of gaps/needs); targeted outreach/education to youth- and adult-focused entities (e.g., pediatricians, schools/universities, primary care providers); expanding screenings to identify risky substance use, alcohol/other drug consumption, suicide risk, and co-occurring disorders; and initiating appropriate evidence-based response. C-SBIRT will utilize age-appropriate, validated pre-screens, such as the National Institute of Drug Abuse’s and National Institute of Alcoholism and Alcohol Abuse’s Single Question Screen, BSTAD, and PHQ-2; validated full screens such as the AUDIT, DAST-10, CRAFFT, PHQ-9/-A, C-SSRS; evidence-based brief intervention via Brief Negotiated Interview and TIP 34: Brief Interventions and Brief Therapies for Substance Abuse; and brief treatment via Cognitive Behavioral Therapy, Motivational Interviewing, and Multi-Dimensional Family Therapy. Case management for those referred to specialty treatment will be guided by TIP 27: Comprehensive Case Management for Substance Abuse Treatment and will include assessment for homelessness risk, peer supports. Project goals include: 1) Implement a project to provide comprehensive, trauma-informed SBIRT services; 2) Implement capacity building to expand and sustain SBIRT services; 3) Improve outcomes among participants receiving brief intervention, brief treatment, and treatment via referrals; and 4) Develop/disseminate a documented service model for statewide replication/adoption. Measurable participant-related objectives include: reduce reported days experiencing mental health symptoms by 40% among those with COD; reduce reported days of opioid use by 50-60% among those with risk at intake; increase abstinence from substance use among 40-60%; reduce inpatient/ER usage among 40%; reduce tobacco use among 60% with risk at intake; increase social connectedness among 70%; assess 100% referred to treatment for wraparound needs and provide 100% with case management; achieve 80% follow up among those referred to treatment. C-SBIRT has secured commitments from collaborators dedicated to the project’s success, and will collaborate with primary care providers, including pediatric providers, schools, and other key community stakeholders.