Summary. The Community Overdose Prevention Education program, led by the North Mississippi Commission on MI/MR with 60 years of proven experience and 4 years expertise as a SAMHSA FR-CARA provider, will save lives from opiate-related overdoses by increasing access to overdose reversal prevention and Medication Assisted Treatment for fentanyl, heroin and other opioids in 17 high-need communities in MS. Population: 1) Populations underserved based on a lack of accessibility to treatment providers, emergency medical services, recovery support services, disproportionately impacted by opioid use; 2) Primary treatment admissions, and 3) Populations with high overdose rates. Strategies: 1) First responders trained on overdose prevention, reversal, and response and Crisis Intervention Team training; 2) Train and provide first responders resources on safety around fentanyl, carfentanil, and other illicit drugs to protect from exposure; 3) Establish processes, protocols, and mechanisms for referral to appropriate treatment and recovery support services, safety around fentanyl, carfentanil, other synthetic opioids, and other licit/illicit drugs associated with overdoses; 4) Use recovery coaches to follow-up with overdose survivors and link to MAT; and 5) Ensure statewide DOH Overdose Prevention Advisory Council advocacy and data-driven oversight. Goals: Reduce fatal and non-fatal overdoses by increase access to overdose prevention reversal and MAT services: 1) Sustain trauma-informed, safety-oriented culturally responsive COPE services; 2) Convene a Diversity, Equity and Inclusion Workgroup to address disparities in underserved communities with culturally responsive targeted outreach promoting access, availability of COPE services; 3) Implement evidence-based services and CIT training to expand first responder capacity to respond safely to individuals experiencing an overdose; 4) Promote Good Samaritan laws, outreach in diverse communities of color, distribute overdose prevention education, social media campaigns; 5) Use recovery coaches to refer individuals surviving an overdose to MAT, establishing warm hand offs with regional CMHCs; and 6) Improve outcomes with data-driven performance measurement and quality improvement. Objectives: Between 9/30/23 and 9/29/27, 1) 80% of OPAC will attend 90% of meetings; 2) Expand access and reduce disparities by monitoring Naloxone Education and Distribution Plan; 3) Expand access to MAT annually for 10% more African Americans; 4)100% of 1,200 first responders trained on safety around fentanyl, carfentanil and other dangerous and illicit drugs; 5) 100% of first responders will be equipped with a drug or device approved or cleared under the Federal Food, Drug, and Cosmetic Act for emergency treatment of known or suspected opioid overdose; 100% will report increased knowledge; 6) 400 opiate related overdoses will be reversed; 7) Respond to 100% of service requests; 8) Increase access to MAT for 100 individuals: 54% African American; 3% Hispanic/Latinx, and/or 3% LGBTQI+ minorities; 85% of first responders trained are sustained. # served: 1,200 first responders (300 annually) and 400 individuals (100 annually) referred for treatment.