The MHAASA of Puerto Rico will implement the PR-SOR 2022 Project to address opioid use Island wide using EBPs. Prevention will focus on experimenting High School Students through the TND EBP, teachers, first responders, corrections officers, SA peers, physicians, and pharmacists through FTS and Naloxone distribution and training. Treatment will focus on SA clients, reaching 1,550 (775 per year) opioid users through MAT, ORP and Wellness Plus, and Recovery will address OUD through ROS with Peer Support and Community Outreach. Prevention Goal 1: Increase state and community capacity to reduce opioid overdose incidence in adults with SUD: Objectives include educating 10,000 SU participants of OTPs, correctional settings and CBOs; Distributing naloxone to 1,800 first responders, correctional officers, SA inmates, pharmacists, Rx technicians, physicians, nurses, and CBO stakeholders in 2 years; Carrying out a MAT public campaign to reduce stigma; Expanding SUD workforce through certification of 140 staff; Capacitating 90,000 participants in ATOD workshops; and Linking to treatment 75% of SUD callers to the PAS Crisis Hotline. Treatment Goal 2: Increase and expand access to drug treatments with FDA approved MAT, including inmates: Objectives include access to 400 new OUD adults in MAT from ER and non-specialty settings with 75% retention; Enhancing EHR of OTPs; HIV/HEP/STD screening and referral; linking of 360 Drug Court Patients to relapse prevention; Initiating naltrexone and injectable buprenorphine treatment for 35 patients in detox; Linking 70 OUD/ODU adults to treatment in CBOs with enhanced psychosocial services; Expanding MAT in Ponce Correctional Institution and SU treatment transition services (ORP) in other settings;. Recovery Goal 3: Ensure access to community recovery support such as peer counseling, recovery coaching and recovery housing: Objectives include use of Wellness Plus EBP for 250 adults in 7 OTPs with positive outcomes in 3 of 5 domains; Integrate 2 Training Facilitators to certify 20 Peer Support Specialist for support to SA treatment; Improve by 5% retention of SU clients through peer support; Expand recover y services to 300 recovering OUD/ODU adults, using contingency management to improve retention; Increase access to telehealth SU treatment in rural and underserved areas; Implement ACT EBP through training of staff serving 150 homeless OUD/ODU adults.