The Puerto Rico (PR) Mental Health and Anti-Addiction Services Administration (MHAASA) proposes a 2-year SOR to reduce opioid addiction and overdose. Under Prevention, Naloxone distribution and training to first responders including Correction Officers and SA Peers; use of PDMP Red Flags for education of patients, physicians and pharmacists; and take-back of controlled medications are proposed. Treatment and Recovery to SA adults will be enhanced with MAT, WRAP, ORP, and RSHT EBP's, including male and parenting offender with OUD. Goal 1 is to reduce opioid overdose incidence in adults with SUD by implementing EB community prevention interventions. Objectives include: distribution of Naloxone with training on use to prevent opioid deaths, to 1,000 first responders, Corrections Officers, and SA Peers, 200 inmates post release and 300 pharmacists, to reduce by at least 15% overdose events in PR. Goal 2 is to increase access for adults with OUD/ODU to FDA approved MAT treatment, including SA inmates. Objectives include: opening 3 new OTP's to give access to MAT to at least 100 new clients with OUD: integrating WRAP EBP to complement MAT for adults with OUD/OD in 8 current, and 3 new, OTP's plus 3 SA Residential Treatment Centers (two for men and one for women), and 5 Drug Court Offices; Implementing a Pilot Project of treatments with Naltrexone and injectable Buprenorphine for 70 adults with OUD/ODU from MHAASA's Detoxification Unit in San Juan, and in SANOS FQHC of Caguas and the Pitirre CBO in Bayamon using physicians with DATA waiver; Implementing an ORP for 60 adults with OUD of the Ponce-500 Correctional Institution with integrated MAT, linking 90% to post-release MAT with recovery support services, and improving parenting skills and family support foe parenting offenders; and Testing 200 newly admitted patients in SA treatment for HIV with referral of positives, and vaccinating 3,000 SA clients at risk of Hepatitis. Goal 3 is to ensure peer counseling and coaching with community support services such as housing to adults with OUD to reduce relapse and criminal re-incidence. Objectives includes: Capacitating and certifying 40 recovered SA adults as Peer Specialist to implement the RTSH EBP with 750 adults with OUD discharged/referred from treatment; Achieving that at least 5% of participants receive stable housing; Provide 160 new enrollees contingency incentives to remain in treatment. This results in a total of 750 trainees receiving Naloxone and education on its use to prevent opioid overdose events per year and 1,500 by project end. It results in a total of 945 adults with OUD/ODU receiving treatment inhanced with EBP's by project end (440 in YR 01); 40 SA peers certified (20 per year) to provide peer counseling and coaching and 750 (375 per year) recovering clients receiving recovery group and RTSH EBP support services. A total 160 (80 per year) of new enrollees will receive contingency incentives to address travel, food and other barriers to participation. An evaluation team will be used to collect, analyze, and report process and outcome data quarterly.