The proposed Ursuline College Breen School of Nursing Medication Assisted Treatment (MAT) Training Integration Project will integrate the full 24 hours of Drug Abuse Treatment Act (DATA) waiver training required for advanced registered practice nurses within the Master of Science in Nursing (MSN) Program. This is an application in response to Funding Opportunity Announcement (FOA) TI-19-011 from the Substance Abuse and Mental Health Services Administration (SAMHSA). The population of focus includes 230 MSN students at the Ursuline College Breen School of Nursing in Ohio, which is the applicant organization. This project is a collaboration between Ursuline College and the University of Pittsburgh School of Pharmacy-Program Evaluation and Research Unit (PERU), St. Vincent Charity Medical Center, and the American Academy of Addiction Psychiatry (AAAP). Key objectives and goals of this project are to increase the number of advanced registered practice nurses who are DATA certified to provide MAT, fully integrate a DATA waiver training curriculum and MAT clinical experience opportunity with MAT providers into the current MSN student curriculum at Ursuline College, increase access to care for OUD in underserved areas in Ohio, and improve clinical coordination and SUD/OUD management. To achieve these objectives, the project will do the following, (1) Ursuline College will integrate the AAAP 24-hour DATA waiver training course for nurses into the MSN curriculum; (2) Ursuline College will provide engaging facilitated discussion in courses so that the self-learning material can be reinforced; (3) St. Vincent will provide the opportunity for students to gain clinical MAT experience under the supervision of an experienced preceptor at specified clinical sites at St. Vincent in Ohio by providing students the opportunity to: (i) conduct patient assessments for OUD, (ii) observe the administration of pharmacotherapy with buprenorphine, naltrexone, and/or methadone, (iii) communicate with patients about their substance use and treatment progression using motivational interviewing, (iv) conduct activities with patients to address diversion and adherence (e.g., urine drug screens), and (v) manage various types of clinical cases and OUD patient populations (e.g., pregnant and postpartum women with OUD, and adults and children with OUD); (4) Ursuline College and PERU will train students in care coordination and SUD/OUD management by optimizing screening, brief intervention and referral to treatment (SBIRT) practices and education; and (5) the project team will collect qualitative and quantitative data to evaluate the outcome and impact of the program and improve the curriculum for future cohorts. This project will span September 2019 to September 2022. This training program will enhance access to high quality treatment for OUD throughout Ohio and the United States by training 230 future healthcare providers to perform buprenorphine pharmacotherapy and manage OUD.