Nebraska Minority Resource Center - Strategic Planning Framework for Tribal Communities - The Nebraska Minority Resource Center (NMRC) Strategic Prevention Framework – Partnerships for Success program will help prevent and reduce substance use among Native American youth and young adults ages 12–24 in four Nebraska Panhandle counties: Box Butte, Cherry, Dawes, and Sheridan. This catchment area has a large concentration of Native Americans, particularly from the Oglala Sioux and Rosebud Sioux tribes, who have migrated to the Nebraska Panhandle from the Pine Ridge and Rosebud reservations (northwest Nebraska and southwest South Dakota, respectively). We (NMRC) will serve Oglala Sioux and Rosebud Sioux youth and young adults, ages 12–24, who are at high risk for early initiation of alcohol and illicit drug use. Because our preventive interventions will be community- and school-based, youth, young adults, and families of other races/ethnicities will benefit. NMRC will use the Strategic Prevention Framework (SPF) to engage community partners to develop and implement a prevention plan. This plan will align the region’s prevention misuse needs with associated risk and protective factors and related social determinants of health, culturally relevant prevention services and supports, and outcomes. We will use the SPF’s five-step process to enhance our capacity to coordinate with state and regional prevention efforts and build the region’s capacity to implement culturally relevant prevention strategies. This will increase the region’s ability to address the needs of Native youth and young adults at risk for substance abuse and their families. The grant will achieve the following goals. (1) Identify and prioritize the substance use prevention needs of Box Butte, Cherry, Dawes, and Sheridan county by collecting, reviewing, and analyzing data. (2) Increase the region’s capacity to address prioritized substance misuse problems in a coordinated, collaborative, and comprehensive manner. (3) Partner with NMRC’s prevention team and youth advisory council to develop a comprehensive plan to increase substance use prevention efforts in the region. (4) Partner with the prevention and youth advisory council to decrease substance misuse in the region by implementing a select set of evidence-informed, culturally relevant, and practical prevention programs and practices. (5) Coordinate with TriWest and prevention partners to collect and analyze data to inform decision-making and increase program effectiveness.