Purpose: Our proposal, Implementing a Trauma-Informed Social-Ecological Approach to Campus Suicide Prevention at UNC Charlotte, adopts a public health approach to suicide prevention among 30,000 college students. In response to several campus and regional traumatic events in recent years, the program seeks to build sustainable trauma-focused, resilience-oriented campus suicide prevention policies, programs, and networks. Populations Served: The following groups are served across program components: (1) faculty, staff, and administration; (2) high risk student groups (i.e., international, graduate, and military-affiliated students); (3) students experiencing stress, mental health and/or substance use concerns; (4) police officers, and; (5) a range of Charlotte, NC area community partners (e.g., VA Medical Center, LGBT youth-serving non-profit). Strategies/Interventions: The following programs will be implemented. First, campus healthcare staff will receive advanced training in brief trauma-focused interventions and evidence-based suicide risk assessment and management practices. Second, QPR gatekeeper training will be vigorously expanded to strengthen certified campus trainers and reach key campus stakeholders (e.g., law enforcement, faculty, military-affiliated students). Third, we will offer an interprofessional education suicide prevention course for health professions students. Fourth, a novel bystander intervention program for problematic drinking will be piloted. Fifth, we will conduct a needs assessment and pilot Niner Resilient, an empowerment and social connectedness enhancement workshop for graduate and international students. Sixth, we will offer annual on-campus mental health screenings. As a culminating activity, we will establish a campus suicide prevention strategic plan, inclusive of a campus-community referral network, in order to sustain and codify grant policies and programs. Project Goals & Objectives: Goal 1 seeks to establish the campus strategic plan and campus-community referral network. Goal 2 will enhance QPR infrastructure by certifying 7 more trainers and offering training to 600 students, staff, faculty and police officers. Goal 3 features training enhancement in advanced trauma-informed and suicide prevention skills for 20 campus health staff and 50 health professions students. Goal 4 will expose 50 students to a new bystander intervention program for problematic drinking. Goal 5 seeks to conduct a needs assessment of 50 graduate and international students, followed by resilience building and social connectedness programming for 50 such students. Goal 6 is to provide on-campus mental health screening for 150 students. The UNC Charlotte team has designed a grant program that responds to the recent traumatic events on the campus and surrounding Charlotte, NC community. Using trauma-informed, social-ecological, and community-academic partnership approaches, this grant will improve the infrastructure needed to identify students in distress, provide evidence-based care, serve high risk groups, innovate in alcohol and suicide prevention programming, and sustain gains achieved over the grant period.