The goal of this project is train all medical, physician assistant, nursing (FNP, DNP), and pharmacy students at Touro University California (TUC) in SUD screening, education, referral, and treatment such that upon graduation they are prepared to enter primary care practice providing care to underserved communities. TUC is a private, not-for-profit university, located in the city of Vallejo within Solano County. Solano County is one of the most racially diverse counties in the US, with high rates of poverty, a 10 year trend in increasing OUD associated emergency department usage, and rising overdose deaths while also being medically underserved. Growing recognition of the opioid epidemic, excessive opioid prescribing practices, and a shortage of access to substance use disorder (SUD) treatments has led to a call for more pain, opioid, and SUD training in health professional schools. This creates an opportunity for health profession schools to reexamine how they train future providers in regards to SUDs with a focus on reducing stigma and closing the treatment gap. For counties like Solano County this means addressing health disparities and foundational access to primary care. TUC focuses on training primary care providers with an emphasis on underserved populations. Recognizing that student attitudes and confidence are best impacted by experiential learning, SUD curriculum will be implemented within the individual health profession program curricula and across the health profession programs through an experiential interprofessional education (IPE) framework that spans the first 2 years of study. We will train 70% of TUC clinical faculty in SUD and IPE competencies required for expansion of the SUD curriculum. An expanded SUD curriculum within each healthcare program will be implemented and include 100% of healthcare students. An innovative IPE SUD experiential curriculum will be implemented and will include 80% of healthcare students. The measurable outcomes will be increased knowledge of SUD, recognition of bias and decreased stigma around SUD, increased confidence in recognizing and managing SUD, increased positive attitude around SUD treatment efficacy, and increased willingness to provide services. Validated measurement tools used include the drug and drug problems perceptions questionnaire (DDPPQ), Short Alcohol and Alcohol Problems Perception Questionnaire (SAAPPQ), SAAPPQ adapted for OUD, marijuana and stimulants, interprofessional professionalism assessment (IPA), Students’ perceptions of interprofessional clinical education revised (SPICE-R). The strength of the current proposal is the foundation in interprofessional SUD education woven together with a public health lens. This framework is rooted in our TUC values of service, diversity, inclusion, and social justice which the foundation for closing the treatment gap for patients with SUD. In year 1, 34 faculty, 135 medical students, 75 pharmacy students, 20 nursing students, and 48 PA students will be served. In year 2, and annually thereafter, >525 students and >250 community members will be served.