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USING WIDEBAND ENERGY REFLECTANCE AND OAES TO ASSESS INFANT MIDDLE-EAR FUNCTION

Award Number: F32DC009939
ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 01/01/2009
PERIOD OF PERFORMANCE END DATE: 08/07/2009

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USING WIDEBAND ENERGY REFLECTANCE AND OAES TO ASSESS INFANT MIDDLE-EAR FUNCTION - DESCRIPTION (provided by applicant): Objective 1: One long term goal is to identify tests that accurately detect middle-ear dysfunction in infants. Wideband (WB) measurements of middle-ear function in infants may overcome limitations of conventional single-frequency middle-ear assessment techniques. Aim 1 of the proposed study evaluates the test performance of conventional 1-kHz tympanometry and WB middle-ear tests (e.g. reflectance, admittance) in terms of their ability to correctly classify pass or refer outcomes on an outpatient otoacoustic emission (OAE) re-screening test. Test performance will be evaluated using clinical decision theory analysis. Identification of a valid test of middle-ear function, which might be used during the newborn hearing screening and follow-up re-screening, would 1) help health care professionals more accurately interpret and communicate OAE and auditory brainstem response (ABR) screening and re-screening test results and 2) improve the accuracy of middle-ear assessment, enabling more informed decisions regarding recommendations for additional diagnostic testing and/or referrals for medical care. Objective 2: Another long term goal is to better understand the effects of age-related changes in the ear-canal and middle-ear on forward and reverse sound transmission between the ear canal and cochlea. Differences in infant and adult OAE responses have been explained by ear-canal and middle-ear effects, but only at 6 kHz. Aim 2 of the proposed study investigates infant middle-ear transmission characteristics using forward and reverse transfer functions between the ear canal and cochlea based on measurements of distortion product (DP) OAEs. Specifically, DPOAE input/output (I/O) functions will be obtained at half-octave frequencies from 1.5 to 8 kHz in adults and young infants with normal hearing function. A model, generated to fit adult DPOAE I/O functions will be used to fit infant functions to calculate forward and reverse transmission gain between the ear canal and cochlea. Changes in transmission gain will be evaluated in infants relative to adults, and across frequency in infants. This information may 1) help interpret age-related changes in OAE responses and 2) inform studies of infant speech perception and hearing sensitivity with regard to potential ear-canal/middle-ear effects. PUBLIC HEALTH RELEVANCE: Results from this study may help improve clinical procedures for the diagnosis and treatment of middle-ear dysfunction in infants. Also, information about how the ear canal and middle ear influence sound as it travels in and out of the ear may help explain developmental differences in clinical hearing test results.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2009 ( Subtotal = -$16,356 )
2009	2008	FATHER FLANAGAN'S BOYS' HOME	14100 CRAWFORD STREET	BOYS TOWN	NE	68010	DOUGLAS	USA	Research Related to Deafness and Communication Disorders	001	1	4/1/2009	NEW	$408
2009	2008	FATHER FLANAGAN'S BOYS' HOME	14100 CRAWFORD STREET	BOYS TOWN	NE	68010	DOUGLAS	USA	Research Related to Deafness and Communication Disorders	002	1	8/4/2009	NEW	-$16,764
2009	2008	FATHER FLANAGAN'S BOYS' HOME	14100 CRAWFORD STREET	BOYS TOWN	NE	68010	DOUGLAS	USA	Research Related to Deafness and Communication Disorders	000	1	12/9/2008	NEW	$0
														Subtotal = -$16,356

Issue Date FY: 2008 ( Subtotal = $49,646 )
2008	2008	FATHER FLANAGAN'S BOYS' HOME	14100 CRAWFORD STREET	BOYS TOWN	NE	68010	DOUGLAS	USA	Research Related to Deafness and Communication Disorders	000	1	8/19/2008	NEW	$49,646
														Subtotal = $49,646

Grand Total All Awards = $33,290

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USING WIDEBAND ENERGY REFLECTANCE AND OAES TO ASSESS INFANT MIDDLE-EAR FUNCTION

Award Number: F32DC009939

ORGANIZATION: NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 01/01/2009

PERIOD OF PERFORMANCE END DATE: 08/07/2009

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