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Cost Effectiveness of Spinal Manipulation Therapy for Seniors with Neck Pain

Award Number: F32AT007507
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 09/01/2014
PERIOD OF PERFORMANCE END DATE: 08/31/2015

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Cost Effectiveness of Spinal Manipulation Therapy for Seniors with Neck Pain - DESCRIPTION (provided by applicant): The long-term objective of this project is to prepare the applicant to become an independent clinical research scientist investigating the clinical and cost effectiveness of spinal manipulation therapy (SMT) for neck and back pain conditions. Brent Leininger, DC, practiced as a chiropractor for three years. He is participating in a bridge fellowship program at Northwestern Health Sciences University (NWHSU), which readies CAM practitioners to pursue research careers. Dr. Leininger's primary sponsor is Dr. Gert Bronfort at Northwestern Health Sciences University, an established clinical researcher in SMT for neck and back pain conditions. During the fellowship period Dr. Leininger will participate in practical research training, formal coursework, and a research project. Practical research experience will be gained through rotations at Dr. Bronfort's clinical research center (Wolfe-Harris Center for Clinical Studies), which will include clinical application of inclusion/exclusion criteria, applicaion of SMT in clinical research, statistical analyses/interpretation, and scientific writing. Collaboration with health economists (co-sponsor Dr. McDonough, consultants Drs. Tosteson and Nyman) at the Dartmouth Institute and the University of Minnesota (U of M) will provide practical research training and mentorship related to the conduct of economic evaluations alongside randomized trials. Formal coursework in clinical and cost effectiveness research at the University of Minnesota will culminate in a Master's of Science degree in Clinical Research and will complement the practical learning experiences. Through the proposed research project, Dr. Leininger will be among the first to assess the economic value of SMT in seniors with chronic neck pain from a societal perspective. Study subjects were those enrolled in his primary sponsor's study (R18HP01425). The applicant's project has three Specific Aims which are complementary to the parent trial and will include an estimation of the cost effectiveness of SMT versus supervised exercise and home exercise for chronic neck pain in seniors using pain, quality-adjusted life years, and disability outcomes over a one-year follow-up period. Through a structured three year training plan, Dr. Leininger will acquire new skills in clinical research of SMT for neck and back pain conditions, as well as cost effectiveness data collection and analytic techniques. This will be fostered by individualized mentorship provided by Dr. Bronfort and co-sponsors (Drs. Evans and McDonough). NWHSU and the University of Minnesota are well suited for the applicant's training and include a CAM focused clinical research center and an NIH affiliated CTSA (1UL1RR033183).


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2017 ( Subtotal = -$2,244 )
2017	2013	NORTHWESTERN HEALTH SCIENCES UNIVERSITY	2501 W 84TH ST	BLOOMINGTON	MN	55431	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	2	1/18/2017	NON-COMPETING CONTINUATION	-$2,244
														Subtotal = -$2,244

Issue Date FY: 2014 ( Subtotal = $78,286 )
2014	2014	UNIVERSITY OF MINNESOTA, OFFICE OF STUDENT FINANCE AID	106 PLEASANT SE, 210 FRASER HL	MINNEAPOLIS	MN	55455	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	3	8/29/2014	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$78,286
														Subtotal = $78,286

Issue Date FY: 2013 ( Subtotal = $70,473 )
2013	2013	NORTHWESTERN HEALTH SCIENCES UNIVERSITY	2501 WEST 84TH STREET	BLOOMINGTON	MN	55431	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	2	7/25/2013	NON-COMPETING CONTINUATION	$70,473
														Subtotal = $70,473

Issue Date FY: 2012 ( Subtotal = $65,563 )
2012	2012	NORTHWESTERN HEALTH SCIENCES UNIVERSITY	2501 WEST 84TH STREET	BLOOMINGTON	MN	55431	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	000	1	7/30/2012	NEW	$53,245
2012	2012	NORTHWESTERN HEALTH SCIENCES UNIVERSITY	2501 WEST 84TH STREET	BLOOMINGTON	MN	55431	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	002	1	8/3/2012	NEW	$0
2012	2012	NORTHWESTERN HEALTH SCIENCES UNIVERSITY	2501 WEST 84TH STREET	BLOOMINGTON	MN	55431	HENNEPIN	USA	Research and Training in Complementary and Integrative Health	001	1	8/3/2012	NEW	$12,318
														Subtotal = $65,563

Grand Total All Awards = $212,078

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Cost Effectiveness of Spinal Manipulation Therapy for Seniors with Neck Pain

Award Number: F32AT007507

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 09/01/2014

PERIOD OF PERFORMANCE END DATE: 08/31/2015

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