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Examining the effects of neighborhood factors and geography on racial/ethnic disparities on achieving sustained viral suppression

Award Number: F31MD015234
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 04/28/2020
PERIOD OF PERFORMANCE END DATE: 01/21/2022

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Examining the effects of neighborhood factors and geography on racial/ethnic disparities on achieving sustained viral suppression - Project Summary/Abstract The risk of HIV transmission and disease progression to AIDS decreases among people living with HIV (PLHIV) that have achieved viral suppression. Prior studies have measured the last viral load in a year to assess viral suppression. However, this single measurement only provides viral suppression status at a single point in time and does not indicate sustained viral suppression throughout a year (all viral load tests within a year <200 copies/mL). Particularly, PLHIV belonging to racial/ethnic minority groups are challenged by barriers to achieving and maintaining viral suppression. Some of these barriers are related to physical and social neighborhood factors such as living in economically deprived neighborhoods. There has been little research to date about the role of neighborhood factors in achieving sustained viral suppression. Therefore, the objective of this F31 study is to assess the contribution of neighborhood, geographic and distance factors on racial/ethnic disparities in sustained viral suppression. To address this objective, secondary data analysis will be conducted using administrative data from the Miami-Dade County Ryan White HIV/AIDS Program, which provides HIV care and treatment to approximately 9,600 underserved and uninsured minority PLHIV. This proposed research study aims to (1) identify individual and neighborhood level factors that are associated with residing in geographic hotspots of low sustained viral suppression, (2) identify the moderating effect of neighborhood disadvantage on the association between race/ethnicity and sustained viral suppression, and (3) examine the moderating effect of race/ethnicity on the association between sustained viral suppression and travel time and distance to HIV case management sites and AIDS Drug Assistance Program pharmacies. The central hypothesis is that neighborhood disadvantage and distance to HIV care facility will contribute to racial/ethnic disparities in achieving sustained viral suppression. The proposed study will use multi-level mixed effects modeling to estimate the association between individual and neighborhood factors and sustained viral suppression and geographic information system tools to identify hotspots of sustained viral suppression and to determine travel time and distance to HIV care facilities. In order to successfully implement this proposed study and launch the research career of a young minority investigator, training in the following 5 areas are proposed: (1) HIV care and treatment disparities, (2) neighborhood and geographic determinants of HIV disparities, (3) multilevel mixed modeling, (4) spatial statistics, and (5) responsible conduct of research and professional development (grant and scientific writing). This study and training experience will facilitate the applicant’s development towards becoming an independent health disparities researcher and provide essential skills to help her successfully compete for a post-doctoral grant or an early career development grant funding. Furthermore, findings from this study will identify neighborhood, geographic, and distance factors that may be targeted to ensure consistent and long-term viral load suppression for vulnerable PLHIV.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$15,557 )
2023	2021	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	2	5/15/2023	NON-COMPETING CONTINUATION	-$15,557
														Subtotal = -$15,557

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2021	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	2	2/23/2022	NON-COMPETING CONTINUATION	$0
2022	2021	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	001	2	3/1/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $34,577 )
2021	2021	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	002	2	4/8/2021	NON-COMPETING CONTINUATION	$0
2021	2021	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	2	2/19/2021	NON-COMPETING CONTINUATION	$34,577
2021	2020	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	001	1	4/8/2021	NEW	$0
														Subtotal = $34,577

Issue Date FY: 2020 ( Subtotal = $34,061 )
2020	2020	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	000	1	4/28/2020	NEW	$34,061
2020	2020	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	002	1	7/23/2020	NEW	$0
2020	2020	FLORIDA INTERNATIONAL UNIVERSITY	11200 SW 8TH ST	MIAMI	FL	33199	MIAMI-DADE	USA	Minority Health and Health Disparities Research	001	1	4/28/2020	NEW	$0
														Subtotal = $34,061

Grand Total All Awards = $53,081

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Examining the effects of neighborhood factors and geography on racial/ethnic disparities on achieving sustained viral suppression

Award Number: F31MD015234

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 04/28/2020

PERIOD OF PERFORMANCE END DATE: 01/21/2022

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