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Daily State-like Distress Tolerance and Alcohol Use Motivation among Hazardous Drinkers with Posttraumatic Stress Disorder

Award Number: F31AA029022
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

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Daily State-like Distress Tolerance and Alcohol Use Motivation among Hazardous Drinkers with Posttraumatic Stress Disorder - PROJECT SUMMARY/ABSTRACT Hazardous drinking and posttraumatic stress disorder (PTSD) are both highly prevalent and frequently comorbid public health conditions that result in more severe clinical and functional outcomes than either individual disorder12-17. There are currently no “gold standard,” evidence-based treatments available for this comorbidity.18 Moreover, the most promising interventions for this population are marked by high rates of attrition and small treatment effect sizes19, leaving this group underserved and lacking a robust and clinically significant intervention20. Some research suggests that individual differences in distress tolerance (DT) are theoretically relevant to both hazardous drinking and PTSD21-25. DT reflects the perceived or objective ability to withstand negative affective or bodily states26. DT is relatively stable (i.e., it has trait-like qualities), but recent work indicates that it also maintains state-like qualities27, 28. State-like DT is a psychological process expressed repeatedly and continuously over time29. Past work has not integrated state-like DT in terms of PTSD and hazardous drinking comorbidity. To fill this gap and facilitate mechanistic knowledge that can inform future treatment development for this population, the proposed research will examine the following primary aims in an ecological momentary assessment (EMA) framework over a 21-day time-sampling epoch: to examine whether state-like lower DT mediates the association between PTSD symptoms at baseline and alcohol use motivation; and whether state-like DT mediates the association between PTSD symptoms at baseline and hazardous drinking. The primary hypothesis of this project is that lower state-like DT will mediate the association between baseline PTSD symptoms and alcohol outcomes listed in A.1.a. and A.2.a. In seeking to identify and understand state-like DT as a mechanism of action that may underly alcohol use and co-occurring conditions (e.g., PTSD), this proposal addresses the National Institute of Alcohol Abuse and Alcoholism (NIAAA) strategic planning goals (Objective 1a). This award will support focused training in research methods and statistical analysis that would not otherwise be possible, as well as provide the opportunity to conduct research to develop a greater understanding of state-like DT as a potential mechanism influencing PTSD- hazardous alcohol use associations.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$37,399 )
2024	2023	UNIVERSITY OF HOUSTON SYSTEM	4300 MARTIN LUTHER KING BLVD	HOUSTON	TX	77204	HARRIS	USA	Alcohol Research Programs	001	3	7/24/2024	NON-COMPETING CONTINUATION	-$12,212
2024	2023	UNIVERSITY OF HOUSTON SYSTEM	4300 MARTIN LUTHER KING BLVD	HOUSTON	TX	77204	HARRIS	USA	Alcohol Research Programs	000	3	10/12/2023	NON-COMPETING CONTINUATION	-$25,187
														Subtotal = -$37,399

Issue Date FY: 2023 ( Subtotal = $38,367 )
2023	2023	UNIVERSITY OF HOUSTON SYSTEM	4300 MARTIN LUTHER KING BLVD	HOUSTON	TX	77204	HARRIS	USA	Alcohol Research Programs	000	3	5/5/2023	NON-COMPETING CONTINUATION	$38,367
														Subtotal = $38,367

Issue Date FY: 2022 ( Subtotal = $37,425 )
2022	2022	UNIVERSITY OF HOUSTON SYSTEM	4800 W CALHOUN ST STE 316	HOUSTON	TX	77004	HARRIS	USA	Alcohol Research Programs	000	2	6/15/2022	NON-COMPETING CONTINUATION	$37,425
														Subtotal = $37,425

Issue Date FY: 2021 ( Subtotal = $36,709 )
2021	2021	UNIVERSITY OF HOUSTON SYSTEM	4800 W CALHOUN ST STE 316	HOUSTON	TX	77004	HARRIS	USA	Alcohol Research Programs	000	1	6/7/2021	NEW	$36,709
2021	2021	UNIVERSITY OF HOUSTON SYSTEM	4800 W CALHOUN ST STE 316	HOUSTON	TX	77004	HARRIS	USA	Alcohol Research Programs	001	1	6/7/2021	NEW	$0
														Subtotal = $36,709

Grand Total All Awards = $75,102

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Daily State-like Distress Tolerance and Alcohol Use Motivation among Hazardous Drinkers with Posttraumatic Stress Disorder

Award Number: F31AA029022

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

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