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Quantifying and reducing upper extremity impairments in cerebral palsy: Biomechanics, hippotherapy, and participation.

Award Number: F30HD104379
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 02/26/2021
PERIOD OF PERFORMANCE END DATE: 08/15/2022

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Quantifying and reducing upper extremity impairments in cerebral palsy: Biomechanics, hippotherapy, and participation. - PROJECT SUMMARY Cerebral Palsy (CP) is the most common childhood motor disability. Spasticity, poor range of motion, weakness, and disuse are hallmarks of upper extremity impairment in CP. Children with CP and their parents report better arm and hand function as a priority. Treatments that are fun, engaging, participation-focused, and challenge the upper extremity in meaningful ways are likely to be the most successful in reducing upper extremity impairments. Hippotherapy (physical therapy on horseback) may offer such an option. In this study biomechanical analysis offers a sophisticated and objective measure of quantifying underlying timing and coordination impairments of the upper extremities; first, as an important comparison between children with CP and typical development (TD) (AIM 1) and second, as a potential outcome measure to quantifying the reduction of upper extremity impairments (and approximation to TD) following hippotherapy intervention (AIM 1a).The long-term goal of my dissertation project is to develop a targeted pediatric rehabilitation treatment (hippotherapy) for children with CP that is engaging, reduces upper extremity impairment, and prevents future decline. This project is grounded in the International Classification of Functioning (ICF) framework. We used 3D motion capture during a functional reach-and-grasp task to measure ICF body structures/functions and activity domains (AIM 1); child- and parent-reported measures of ICF activity and participation domains (AIM 2), and the application of these measure to assess a hippotherapy intervention (AIM 1a, AIM 2a). Last, we propose to explore the feasibility of applying measures of patient engagement and enjoyment as ICF personal factors during hippotherapy intervention (AIM 3). We anticipate these measures might cast a window into why hippotherapy is potentially effective. We have demonstrated the ability to measure adherence to a hippotherapy treatment protocol and to execute the reach-and-grasp protocol with children with CP and TD. Through these aims, we will test the overarching hypotheses that 1) children with CP demonstrate slower and less-coordinated reach and grasp in a functional task and poor participation compared to their TD peers and 2) these measures can evaluate change in a hippotherapy intervention, and 3) child engagement and enjoyment of hippotherapy can be quantified. The results of this investigation will guide future study design for hippotherapy clinical trials. With the guidance of my interdisciplinary sponsorship team, the preparation, enactment, analysis, and dissemination of this project will enable me to achieve the goals of my dual-degree program and catapult me to becoming a productive, independent clinician-scientist.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = -$36,262 )
2023	2022	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	002	2	6/20/2023	NON-COMPETING CONTINUATION	-$20,181
2023	2022	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	001	2	3/30/2023	NON-COMPETING CONTINUATION	$0
2023	2022	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	000	2	3/22/2023	NON-COMPETING CONTINUATION	-$16,081
														Subtotal = -$36,262

Issue Date FY: 2022 ( Subtotal = $42,518 )
2022	2022	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	003	2	5/27/2022	NON-COMPETING CONTINUATION	-$1
2022	2022	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	001	2	4/27/2022	NON-COMPETING CONTINUATION	$717
2022	2022	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	002	2	5/13/2022	NON-COMPETING CONTINUATION	$0
2022	2022	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	000	2	1/20/2022	NON-COMPETING CONTINUATION	$41,802
														Subtotal = $42,518

Issue Date FY: 2021 ( Subtotal = $41,136 )
2021	2021	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	000	1	2/26/2021	NEW	$41,136
2021	2021	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Dietary Supplement Research Program	001	1	2/26/2021	NEW	$0
														Subtotal = $41,136

Grand Total All Awards = $47,392

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Quantifying and reducing upper extremity impairments in cerebral palsy: Biomechanics, hippotherapy, and participation.

Award Number: F30HD104379

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 02/26/2021

PERIOD OF PERFORMANCE END DATE: 08/15/2022

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