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The Role of Neighborhood- and Facility-Level Factors in Pediatric Sepsis Mortality

Award Number: F30HD100074
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 02/01/2020
PERIOD OF PERFORMANCE END DATE: 01/31/2023

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The Role of Neighborhood- and Facility-Level Factors in Pediatric Sepsis Mortality - PROJECT SUMMARY/ABSTRACT Pediatric sepsis affects over 50,000 U.S. children each year, resulting in long-term functional disability and higher risk of mortality at a cost of nearly $2 billion. Early recognition and resuscitation of pediatric sepsis can reduce mortality and improve outcomes. However, current adherence to early resuscitation guidelines remains low among pediatric sepsis and septic shock patients. Adherence to pediatric sepsis care guidelines is worse than in the adult sepsis population, especially in low-volume facilities. Compared to adults, pediatric sepsis patients may be at higher risk of disparate incidence and outcomes given sparser access to definitive pediatric hospital care. The central hypothesis of this study is that increased pediatric sepsis mortality can be partially attributed to geographic access and facility-level characteristics among patients with similar severities of illness. This study will use multi-state all-payer administrative claims data and a national readiness survey of emergency departments (EDs) to test the central hypothesis with the following aims: (1) identify facility-level characteristics associated with effective pediatric sepsis care and (2) determine the role of access to care in pediatric sepsis outcomes. The proposed work will provide a foundation of evidence to inform the development of pediatric sepsis quality improvement programs and systems for pediatric populations with decreased access to children’s hospitals. This research training project will equip Morgan Swanson (Principal Investigator) with the research experience, advanced critical thinking skills, and technical knowledge to succeed as an independent investigator. As a future physician-scientist, this project will provide Ms. Swanson with foundational skills to develop a research career focused on minimizing the burden of pediatric critical illness through improving emergency health care access and delivery.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	THE UNIVERSITY OF IOWA	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	3	12/28/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $39,893 )
2022	2022	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	3	1/21/2022	NON-COMPETING CONTINUATION	$39,177
2022	2022	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	3	7/7/2022	NON-COMPETING CONTINUATION	$716
														Subtotal = $39,893

Issue Date FY: 2021 ( Subtotal = $39,222 )
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	2	3/18/2021	NON-COMPETING CONTINUATION	$516
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	002	2	6/24/2021	SUPPLEMENT FOR EXPANSION	$2,500
2021	2021	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	2	1/25/2021	NON-COMPETING CONTINUATION	$36,206
														Subtotal = $39,222

Issue Date FY: 2020 ( Subtotal = $36,206 )
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	002	1	2/12/2020	NEW	$0
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	000	1	1/29/2020	NEW	$35,702
2020	2020	UNIVERSITY OF IOWA, THE	105 JESSUP HALL	IOWA CITY	IA	52242	JOHNSON	USA	Child Health and Human Development Extramural Research	001	1	2/12/2020	NEW	$504
														Subtotal = $36,206

Grand Total All Awards = $115,321

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The Role of Neighborhood- and Facility-Level Factors in Pediatric Sepsis Mortality

Award Number: F30HD100074

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 02/01/2020

PERIOD OF PERFORMANCE END DATE: 01/31/2023

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