Building on 17 years of providing culturally resonant trauma-responsive mental health screening, mental health services, and school-based psycho-education to Black youth and their families in Louisiana in the aftermath of Hurricane Katrina, the Institute of Women & Ethnic Studies (IWES) proposes to improve the mental health outcomes and reduce suicidality among Black youth in New Orleans by assessing and disseminating recommendations for implementing high-impact policies in schools, the juvenile legal system, public health, healthcare, and social services settings. IWES is requesting support from the Office of Minority Health (OMH) Demonstrating Effective Policies to Promote Black Mental Health (MP-CPI-22-001) to implement Multisystem Compassionate Care and Healing for Black Youth (MCH-BY) with a focus on screening, macro-level interventions to improve societal conditions, training approaches to address institutional racism, and clinical approaches to address the impact of racism and racial trauma on youth and families. MCH-BY will be implemented with cross-sector stakeholders, including advocates from National Alliance of the Mentally Ill (NAMI), Black youth and caregivers. This is a collaborative that will engage Core Implementation Partners, an Advisory Council, and Youth Ambassadors who will provide governance and guidance on policy identification and assessment, strategic reform and implementation of selected high impact policies, and effective strategies to support sustainable policy change.