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BRF: MSK Center for Precision Theranostics – Monmouth, NJ

Award Number: C06OD042699
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: CONSTRUCTION
PERIOD OF PERFORMANCE START DATE: 09/18/2026
PERIOD OF PERFORMANCE END DATE: 09/30/2028

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BRF: MSK Center for Precision Theranostics – Monmouth, NJ - PROJECT SUMMARY/ABSTRACT The proposed project will establish the Center for Precision Theranostics through the construction of a 9,464- square-foot collaborative research facility in existing shell space in one of Memorial Sloan Kettering Cancer Center (MSK)’s regional sites, MSK Monmouth in Middletown, New Jersey. Theranostics combines therapy and diagnostics by using a single molecular vector to deliver both a diagnostic signal and a therapeutic payload to the same biological target. Basic and translational research across disease-site groups across MSK and collaborating academic institutions has developed a portfolio of high-impact candidates for theranostic applications. However, the capacity to safely and reliably evaluate them is increasingly limited, resulting in a bottleneck that prevents NIH-supported innovation in molecular imaging, medical physics/radiation safety, medical and radiation oncology, and early drug development from being translated into theranostic indications for patients with cancer. The proposed Center will feature: (1) licensed treatment suites designed for outpatient radiopharmaceutical administration; (2) housing for PET/CT and SPECT/CT imaging to enable baseline selection and post-therapy verification/dosimetry; (3) a radiopharmacy with validated receiving, compounding, aseptic processing, and quality control workflows; (4) radiation safety engineering controls (shielding, decay-in-storage, monitored waste streams); and (5) operational infrastructure to run multiple concurrent investigational protocols. The overarching goal of the Center is to advance the most promising cancer theranostic agents through early- phase trials, establish the endpoints needed for registration through an integrated biomarker discovery and validation platform, and propel lead candidates into phase 3 testing and regulatory approval. Objectives will support institutional strategic priorities by addressing a critical gap in access to potentially life-saving theranostics clinical trials for an underserved regional population in New Jersey and extending MSK’s national leadership in radiotheranostics innovation. Long-term impact will be enhanced by the dissemination of a comprehensive guide for the design, construction, equipment, and operations of a theranostics center, reducing the barrier to entry for institutions nationwide. The creation of a regional hub for training the next generation of physician-scientists in theranostics, will complement MSK's existing NIH-funded training grants and residencies and fellowships in Molecular Imaging and Therapy, Radiation Oncology, and Medical Physics. The Construction Project Manager and the institution’s Planning, Construction & Design team will work closely with the external construction partner to oversee the project. The President and CEO of MSK, with delegated authority from MSK’s Board of Trustees to commit financial resources and ongoing operational support, will serve as the PD/PI.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $7,892,852 )
2026	2026	SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH	1275 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Construction Support	000	1	9/17/2026	NEW	$7,892,852
														Subtotal = $7,892,852

Grand Total All Awards = $7,892,852

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BRF: MSK Center for Precision Theranostics – Monmouth, NJ

Award Number: C06OD042699

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: CONSTRUCTION

PERIOD OF PERFORMANCE START DATE: 09/18/2026

PERIOD OF PERFORMANCE END DATE: 09/30/2028

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