The proposed project will renovate North Carolina Agricultural and Technical State University’s (NCA&T)
38- year-old vivarium for use as a core research facility serving the university community and the
Piedmont Triad region in central NC. This renovation is critically needed to address the vivarium’s
structural and design issues that make it challenging to meet the needs of biomedical researchers, a
group whose numbers are increasing at our institution. The requested funding will help drive this
increase in biomedical research, breaking the Catch-22 predicament that limits faculty submission of
federal grant proposals for research with animal subjects and constrains further expansion of our
institution’s biomedical research enterprise. As a result of the vivarium’s outdated status, our
researchers are using other facilities or changing their research agendas to alternative models. To
reverse this trend and align with the university’s strategic plan and stated intent to attain R1 status, the
project goals are to (1) renovate and redesign the existing vivarium to provide a modern
environmentally-controlled unit, with noise reduction and an efficient cage washing facility and traffic
pattern and (2) to create a near barrier facility with fixed exhaust ventilated cages and biological safety
cabinets. Long-term impact of the proposed renovation will enable the expansion of biomedical, life
science, and agricultural research at NCA&T and the Piedmont Triad region, which is home to a growing
number of companies in the biosciences, pharma, and healthcare; and increase the advancement of
undergraduate, doctoral and post-doctoral research training to increase regional, statewide and
national diversity within biomedical sciences and careers.
Renovation of the vivarium will enhance research programs across the institution by providing the
resources needed to conduct biomedical research projects on campus in a core research animal facility
versus seeking animal housing and ancillary support at other facilities. The renovated facility will also
support increased research productivity by encouraging faculty to seek targeted external funding to
grow their biomedical research portfolios incorporating animal models and by promoting recruitment of
new research faculty with biomedical research interests. Additionally, the project will help us accomplish
our long-term goal of achieving AAALAC accreditation.
Per the four criteria at U.S.C. 42 Section 283k(c)(2), NCA&T declares its status as an Institution of
Emerging Excellence (IEE). The renovated vivarium will help NCA&T elevate its status from an NIH-
designated IEE to a research-intensive institution.