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Significant expansion of the SNPRC Specific Pathogen Free Rhesus Macaque Colony for AIDS research

Award Number: C06OD030079
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: CONSTRUCTION
PERIOD OF PERFORMANCE START DATE: 09/01/2021
PERIOD OF PERFORMANCE END DATE: 05/31/2026

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Significant expansion of the SNPRC Specific Pathogen Free Rhesus Macaque Colony for AIDS research - The Southwest National Primate Research Center (SNPRC) SPF rhesus colony, supported by the NIH SPF rhesus breeding program (U42 OD010442), is presently around 900 animals and supports AIDS-related research both at SNPRC and through sales to AIDS investigators at other institutions. The SNPRC is well positioned to maintain and expand SPF rhesus macaque production as a center located in a climate hospitable to largely outdoor housing at an institution with capacity for expansion. The NIH has recently recognized the need for expansion of SPF rhesus production. Specifically, the ORIP Nonhuman Primate Evaluation and Analysis completed in December, 2018, proposes providing “NIH resources to expand existing colonies of rhesus macaques, including SPF and enhanced SPF colonies, by 10-25% in order to meet growing demand” as one of eight key recommendations stemming from the expert panel discussions (https://orip.nih.gov/about- orip/research-highlights/nonhuman-primate-evaluation-and-analysis-part-2-report-expert-panel). This application proposes renovation and new construction in one of two SPF rhesus housing complexes that will significantly expand our capacity to produce SPF rhesus macaques for use in AIDS research and will enhance our ability to manage the population for research use in the most efficient and humane fashion. The proposed renovation will increase our capacity to produce SPF rhesus macaques by 41%; provide appropriately designed space to allow for examination and sampling of animals destined for potential study or sale while not completely removing them from their original social setting; minimize the need to move animals away from the building complex by providing a modern clinic and processing rooms in association with the housing complex; improve the care of animals during the holding and recovery phase of processing by expanding the number of animals processing holding bays. Highlights of the proposed renovation include improving cage wall and ceiling materials both within the sheltered or indoor areas and the outdoor areas in order to make the cages suitable for housing rhesus macaques, providing fully enclosed “conditioned” holding space for exams and sampling, and making sustainable and environmentally-sensitive facility improvements that will last at least the next 20 years. Our proposal will ensure that existing animals are adequately housed and cared for during the renovation.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Construction Support	000	1	9/8/2026	NEW	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Construction Support	001	1	1/30/2023	NEW	$0
2023	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Construction Support	000	1	11/2/2022	NEW	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $1,996,771 )
2021	2021	TEXAS BIOMEDICAL RESEARCH INSTITUTE	8715 W MILITARY DR	SAN ANTONIO	TX	78227	BEXAR	USA	Construction Support	000	1	9/1/2021	NEW	$1,996,771
														Subtotal = $1,996,771

Grand Total All Awards = $1,996,771

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Significant expansion of the SNPRC Specific Pathogen Free Rhesus Macaque Colony for AIDS research

Award Number: C06OD030079

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: CONSTRUCTION

PERIOD OF PERFORMANCE START DATE: 09/01/2021

PERIOD OF PERFORMANCE END DATE: 05/31/2026

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