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Efficacy of tele-CPASS, a telerehabilitation intervention using Critical Periods After Stroke (CPASS), compared to in-person CPASS therapy for upper extremity motor recovery.

Award Number: 90IFST0026
ORGANIZATION: NATIONAL INSTITUTE ON DISABILITY, INDEPENDENT LIVING, AND REHABILITATION RESEARCH
OPDIV: ACL
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 09/01/2025
PERIOD OF PERFORMANCE END DATE: 08/31/2028

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Efficacy of tele-CPASS, a telerehabilitation intervention using Critical Periods After Stroke (CPASS), compared to in-person CPASS therapy for upper extremity motor recovery. - Nearly two-thirds of the 800,000 annual stroke survivors experience persistent upper extremity (UE) motor impairments. In the Critical Periods After Stroke Study (CPASS), we demonstrated that rehabilitation is time-sensitive—patients receiving therapy within 0–4 months post-stroke recover significantly better than those starting at 6 months. Despite this, rehabilitation dose declines sharply after inpatient discharge at 1 month, not due to full recovery but logistical barriers. Significance: Access to intensive stroke rehabilitation is particularly limited in areas where geographic, financial, and transportation barriers prevent timely intervention. El Paso, TX exemplifies this challenge. Telerehabilitation offers a scalable solution by delivering therapy directly to patients in their homes. Goals & Approach: We propose a longitudinal, single-blind, randomized controlled, non-inferiority trial to evaluate tele- CPASS, a telerehabilitation adaptation of CPASS, against in-person CPASS during the critical recovery window. Thirty-eight patients will be randomized within <40 days post-stroke to receive 20 hours of therapy over 30 days via tele-CPASS or in person CPASS. Outcomes include the Action Research Arm Test (ARAT), and accelerometry-based arm use in daily life, tested at Baseline, post-intervention and six-months post stroke. Expected Outcomes & Impact: If successful, tele-CPASS can be integrated into standard care using existing CPT codes for telerehabilitation, ensuring access to high-quality stroke rehabilitation. This scalable, patient-centered model has national implications for improving stroke recovery outcomes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $249,831 )
2026	2026	THE UNIVERSITY OF TEXAS AT EL PASO	500 W UNIVERSITY AVE	EL PASO	TX	79968	EL PASO	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	00	2	9/2/2026	NON-COMPETING CONTINUATION	$249,831
														Subtotal = $249,831

Issue Date FY: 2025 ( Subtotal = $249,999 )
2025	2025	THE UNIVERSITY OF TEXAS AT EL PASO	500 W UNIVERSITY AVE	EL PASO	TX	79968	EL PASO	USA	ACL National Institute on Disability, Independent Living, and Rehabilitation Research	00	1	7/7/2025	NEW	$249,999
														Subtotal = $249,999

Grand Total All Awards = $499,830

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Efficacy of tele-CPASS, a telerehabilitation intervention using Critical Periods After Stroke (CPASS), compared to in-person CPASS therapy for upper extremity motor recovery.

Award Number: 90IFST0026

ORGANIZATION: NATIONAL INSTITUTE ON DISABILITY, INDEPENDENT LIVING, AND REHABILITATION RESEARCH

OPDIV: ACL

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 09/01/2025

PERIOD OF PERFORMANCE END DATE: 08/31/2028

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